Publications by authors named "Matas Sereika"
Article Synopsis
- - Cell signaling manipulation is crucial for cancer treatment, with the relationship between cell state and drug response being vital for developing effective therapies tailored to individual patients.
- - The study examined how non-oncogene dependencies influence lung cancer cell resistance to treatments by investigating the interaction between MEK/ERK and PI3K/AKT pathways using patient-derived cell lines with different characteristics.
- - Researchers found that inhibitors of MEK/ERK increased AKT activation and vice versa, indicating that these pathways communicate in response to these inhibitors, but the nature of this interaction varies based on the cellular environment and state.
