Subungual exostosis is a benign calcifying projection that occurs on the distal phalanx beneath or beside the nail. The problems in treatment are frequent postoperative recurrence and nail deformity or loss. Here, we describe the case of a male patient with a subungual exostosis beneath the proximal region of the nail plate of the right big toe.
View Article and Find Full Text PDFRepetitive mechanical activity induces a cutaneous reaction. A 22-year-old male presented with painful hyperkeratosis on the right heel. The hyperkeratosis had gradually developed after taking up the practice of Kendo.
View Article and Find Full Text PDFMultiple pilosebaceous cysts include the entities of steatocystoma multiplex and eruptive vellus hair cysts (EVHCs). Multiple pilosebaceous cysts are proposed to be one entity originating in the pilosebaceous duct, since steatocystoma multiplex and EVHCs are frequently present concomitantly and are caused by a cystic change in the same pilosebaceous duct. Here, we describe a patient with yellowish papules, 3-8 mm in diameter, on the neck and skin-colored or light-brown papules, 1-3 mm in diameter, on the neck, chest and upper abdomen.
View Article and Find Full Text PDFAmelanotic vulvar melanoma is a rare type of malignant melanoma. This paper describes a case of an asymptomatic ulcerated nodule 20 mm in size. The tumor cells from the nodular lesion showed positive staining immunohistochemically for Melan-A, but negative staining with HMB-45.
View Article and Find Full Text PDFWe obtained an antibody, anti-inner root sheath cells antibody (anti-IRSC Ab), that reacted with the inner root sheath (IRS) cells especially trichohyalin granules (THG). In order to compare the properties of anti-IRSC Ab and AE15, which is a specific monoclonal antibody against THG, histochemical and biochemical examinations were performed. In vivo localization with anti-IRSC Ab and AE15 indicated that both antibodies reacted with THG, but anti-IRSC Ab reacted with THG in the suprabulbar region of the Huxley layer, whereas AE15 reacted with THG in the suprabulbar region and upper bulbar portion of the Huxley layer, as shown by immunohistochemical and immunoelectron microscopic analyses.
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