Clinical spectrum of eye malformations in four patients with Mowat-Wilson syndrome.

Mowat-Wilson syndrome (MWS) is a rare genetic syndrome characterized by a specific facial gestalt, intellectual deficiency, Hirschsprung disease and multiple congenital anomalies. Heterozygous mutations or deletions in the zinc finger E-box-binding homeobox2 gene (ZEB2) cause MWS. ZEB2 encodes for Smad-interacting protein 1, a transcriptional co-repressor involved in TGF-beta and BMP pathways and is strongly expressed in early stages of development in mice.

[Final visual acuity in patients undergoing posterior vitrectomy for Terson's syndrome: a series of 11 cases].

Purpose: The purpose of this study was to assess visual acuity after vitrectomy for Terson's syndrome.

Methods: This is a retrospective study of 11 eyes (7 patients), who underwent pars plana vitrectomy between 1996 and 1998. Visual acuity was evaluated at 1, 5 and 12 months.

[Non-penetrating deep sclerectomy in the surgical treatment of chronic open-angle glaucoma. Mid-term results].

Purpose: Non-penetrating deep sclerectomy has been performed in France since the early nineties and appears to be an interesting alternative to Cairn's trabeculectomy. The technical characteristics, the ability to use antimitotic procedures and postoperative YAG laser goniotomy contribute to make deep sclerectomy an attractive surgical method. We evaluated its efficacy and adverse effects in a mid-term retrospective series.

Effects of low alcohol consumption on visual evoked potential, visual field and visual contrast sensitivity.

Purpose: We studied changes in the vision of 16 people after consumption of a small quantity of alcohol, at a blood alcohol level (BAL) of 0.57 g/kg.

Methods: We studied visual contrast sensitivity (VCS) using Vistech VCTS 6500, visual evoked potential (VEP) by checked pattern stimulations and the peripheral visual field (PVF) with a perimetric automatic Humphrey.

[Apropos of a rare case of bilateral orbital metastasis of malignant melanoma of the choroid].

We report a case of bilateral orbital metastasis from an ocular choroidal melanoma which had required enucleation eight years earlier. This uncommon case was fully documented with clinical, radiological and pathological studies. Magnetic resonance imaging was particularly contributive showing very characteristic sequences.

[The role of percutaneous puncture alcohol sclerotherapy in the treatment of symptomatic kidney cysts].

Objective: The objective of this study was to prospectively evaluate the results of percutaneous alcohol sclerotherapy of symptomatic renal cysts in adults.

Material And Methods: We report a series of 13 patients with a mean age 69 years (47-75 years). The operative indication was pain (9 cases), urinary tract compression (3 cases), very large cyst (1 case).