Human papillomavirus infection and non-oropharyngeal head and neck cancers: an umbrella review of meta-analysis.

Objective: The causative and prognostic roles of human papillomavirus (HPV) in non-oropharyngeal squamous cell carcinoma of the head and neck are uncertain. This umbrella review assessed the strength and quality of evidence and graded the evidence derived from published meta-analyses on this subject.

Data Sources: MEDLINE, Embase, and the Cochrane Library were searched.

Look at the elephant! Commentary on 'Prevalence of temporomandibular disorders in adult obstructive sleep apnoea patients: A cross-sectional controlled study'.

The relationship between obstructive sleep apnoea (OSA) and temporomandibular disorders (TMDs) is complex. Research has shown controversial evidence. The recent study by Bartolucci et al.

Comparison of different treatments for HPV+ oropharyngeal carcinoma: a network meta-analysis.

Introduction: Treatment of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is rapidly evolving. Despite either surgery or radiotherapy (RT), with or without chemotherapy (CT), being acceptable in intermediate and locally advanced diseases, there is uncertainty regarding the best treatment option for these patients. Therefore, we performed a network meta-analysis (NMA) to compare the relative efficacy of different treatments for HPV+ oropharyngeal carcinoma.

Myringoplasty in simple chronic otitis media: critical analysis of long-term results in a 1,000-adult patient series.

Objectives: Investigate the recurrence of chronic otitis media after primary and revision myringoplasty, compare long-term anatomic and audiologic results of underlay and overlay myringoplasty, and examine the prognostic factors.

Study Design: Retrospective study.

Patients: Approximately 1,040 adult patients with chronic simple otitis media undergoing a myringoplasty (overlay and underlay) by different surgeons at a single institution (ENT Department of Bergamo Ospedali Riuniti) between May 1999 and March 2009.

Dornase alfa as postoperative therapy in cystic fibrosis sinonasal disease.

Objective: To determine the benefit of nasally inhaled dornase alfa in patients with cystic fibrosis and nasal symptoms.

Design: Double-blind placebo-controlled trial.

Setting: Cystic Fibrosis Regional Center of Campania at the University of Naples "Federico II.

Connexin 26 mutations in nonsyndromic autosomal recessive hearing loss: speech and hearing rehabilitation.

Objective: Hearing loss is the most common form of sensory impairment, with approximately one infant/1000 born with profound congenital deafness. A pre-lingual bilateral sensorineural hearing impairment poses a substantial problem as it negatively impacts on the subject's ability to conduct a normal social life. The aim of the study was to observe, in a group of children affected by pre-lingual non-syndromic autosomal recessive hearing impairment: (1) the role of the possible mutation of connexin 26 in the pathogenesis of the hearing loss; (2) the audiological and clinical aspects of the hearing impairment; (3) therapy to be adopted for the different patients.

The 11th nerve syndrome in functional neck dissection.

Objectives: Assessment of the incidence of shoulder joint disability and evaluation of the role of a personal postoperative physical rehabilitative protocol therapy in reducing pain and shoulder dysfunction and improving the quality of life (QOL) of patients who have undergone functional neck dissection (FND) associated with total laryngectomy. SETTING, DESIGN, AND OUTCOME MEASURES: Sixty laryngectomees who had undergone FND were divided into two groups (A and B). Group A received physical therapy after surgery.