Publications by authors named "Massimiliano Messina"
Article Synopsis
- - Vascular Ehlers-Danlos syndrome (vEDS) is a rare genetic disorder caused by mutations in the gene for type III collagen, leading to fragile blood vessels and serious complications like aneurysms or ruptures, particularly affecting medium-sized arteries.
- - Previously, vEDS was associated with a high mortality rate and an average life expectancy of around 50 years, but recent advancements in medical awareness and treatment have improved patient outcomes significantly.
- - Current treatments, particularly the use of celiprolol, a specific heart medication, have shown promise in reducing vascular incidents in vEDS patients; however, more research is needed to fully understand its benefits, and other potential therapeutic avenues are being explored for future treatment. *
BACKGROUND The aim of this study was to assess the long-term effects of smoking and to investigate the permanence of this damage to the oral microcirculation. MATERIAL AND METHODS We recruited 75 patients and divided them into 3 groups: group 1 was composed of 25 healthy non-smokers, group 2 was composed of 25 healthy current smokers, and group 3 was composed of 25 healthy ex-smokers. Video-capillaroscopic examination was performed on all patients.
View Article and Find Full Text PDFNutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
December 2016
Background: Microbiota refers to the population of microorganisms (bacteria, viruses and fungi) that inhabit the entire gastrointestinal tract, more particularly the colon whose role is to maintain the integrity of the intestinal mucosa and control the proliferation of pathogenic bacteria. Alteration in the composition of the gut microbiota is called dysbiosis. Dysbiosis redisposes to inflammatory bowel diseases such as ulcerative colitis, Crohn disease and indeterminate colitis.
View Article and Find Full Text PDF