Publications by authors named "Massimiliano Giuffrida"

Key Clinical Message: can cause rare odontogenic brain abscesses in immunocompetent patients, highlighting the importance of considering uncommon pathogens in central nervous system infections. With only three reported cases of cerebral abscesses and one pituitary abscess caused by this microorganism, tailored diagnostic methods and individualized treatment regimens are crucial for accurate management.

Abstract: Brain abscesses present diagnostic and therapeutic challenges, with infections being exceptionally rare in the central nervous system.

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Introduction: Pedicle screw placement is a widely accepted surgical procedure for spinal fixation. Despite increases in knowledge about and expertise in pedicle screw insertion techniques, overall reported screw misplacement rates are still high. Spinal neuronavigation and intraoperative computed tomography (CT) imaging improves the accuracy and safety of pedicle screw placement through the continuous monitoring of screw trajectory.

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Background: Frontotemporal dementia (FTD) is a highly disabling neurologic disorder characterized by behavioral alterations and movement disorders, involving patients with a mean age of 58 years. We present a unique case of a patient suffering from FTD who developed post traumatic bilateral hygromas.

Case Description: A 52-year-old male patient, with an history of head trauma 3 months before, was admitted to our department for recurrent motor seizures.

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Background: Neurofibromatosis Type 1 (NF-1) and previous irradiation are two common risk factors that can result in malignant peripheral nerve sheath tumors (MPNSTs), extremely rare soft-tissue sarcomas. Here, a 63-year-old male with NF-1 presented with diffuse spinal metastases from a subcutaneous MPNST.

Case Description: A 63-year-old male with NF-1 presented acutely with paraplegia and urinary incontinence.

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Article Synopsis
  • * A case involved a 54-year-old woman with an L2-L5 spinal epidural abscess linked to a previous kidney infection, who experienced significant back pain and leg weakness.
  • * After surgical intervention to drain the abscess and targeted antibiotic treatment, the patient improved and was able to walk upon discharge 15 days later.
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Article Synopsis
  • - Chronic encapsulated intracerebral hematoma (CEICH) is a rare condition that appears as a slowly growing mass in the brain, often causing neurological symptoms like increased intracranial pressure, seizures, and motor deficits, with most cases showing atypical locations.
  • - A systematic review analyzed 40 studies involving 58 patients to evaluate diagnosis and management strategies for CEICH, noting that the average age of patients was around 41 years and that surgical methods varied, with craniotomy being the most common approach (53.4%).
  • - The study found no correlation between CEICH and patients taking anticoagulants or antiplatelets, with arteriovenous malformations being the leading cause; further research is needed
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Background: Epidural dumbbell-shaped chordomas are localized slow growing, and malignant/aggressive neoplasms. Here, we present a 62-year-old male with a T3-T4 dumbbell-shaped chordoma and reviewed the appropriate literature.

Case Description: A 62-year-old male presented with a three-month history of thoracic pain.

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Background: Chronic subdural hematoma (cSDH) represents a complex and unpredictable disease, characterized by high morbidity and mortality, especially in elderly patients. Factors affecting the postoperative brain reexpansion along to cSDH recurrence have not been yet adequately investigated. The authors presented the case of a schizophrenic patient affected by trabecular type cSDH that presented a delayed brain reexpansion despite a craniotomy and membranotomy.

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Background: Tethered spinal cord syndrome (TCS) can occur after the surgical repair of lipomeningoceles (LMCs). In these cases, the tethering results from postoperative adhesions between the spinal cord and the overlying repaired dura. A watertight dural closure using the residual dura and/or the surrounding tissues does not always provide enough space for the spinal cord and risks retethering.

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Background: Burkitt's lymphoma is a non-Hodgkin B-cell lymphoma, occurring mostly in Equatorial Africa. According to the WHO, classification is three different variants: sporadic, endemic, and immunodeficient-associated. Here, we present a patient with "sporadic" primary epidural Burkitt's lymphoma resulting in chronic low back pain (LBP).

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Background: The treatment of spontaneous spinal epidural hematomas (SSEHs), depending on the lesion size and myeloradicular involvement, can be surgical or conservative. Here, we present a 55-year-old patient who sustained a SSEH several months following a systemic SARS-CoV-2 infection.

Case Description: A 55-year-old immunocompromised female (i.

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Background: Extraforaminal lumbar disc herniation (ELDH) amounts of 7%-12% of all lumbar disc herniations. Although they have already been widely described, an optimal treatment is still under discussion in the literature.

Objective: We describe a novel application of navigation using 2D/3D imaging system to plan an adequate surgical trajectory and performing a neuronavigated microdiscectomy in ELDH that has not been previously described.

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Background: Nontuberculous mycobacteria (NTM) represents an important cause of infection, particularly in immunocompromised patients. Spondylodiscitis is unusual and may be associated with underlying causes such as drug abuse. Timely diagnosis and treatment are critical, as without this, patients will demonstrate progressive neurological deterioration.

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Background: Diffuse large B-cell lymphoma (DLBCL) in rare cases can presents an unusual expression of CD3 T-cell specific antigen. We report the first case of a CD3-positive DLBCL of the cervico-thoracic junction presenting with persistent cervical radiculopathy.

Case Presentation: A 74-years-old male patient presented a severe and persistent right C8 radiculopathy associated with right-sided neck pain, progressive numbness and weakness of the right arm.

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Article Synopsis
  • A 78-year-old male presented with severe neck pain and progressive weakness, and MRI revealed a 10 mm×15 mm lesion in the C1-C2 region linked to a large RCC mass in the kidney.
  • After surgical removal of the spinal lesion, the patient showed slight motor improvement but ultimately succumbed to the disease 14 months later, underscoring the importance of proper staging in treatment decisions for unknown RCC presentations.
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Background: Intradural disc herniations (IDHs) are rare occurrences (0.26-0.30%), and most frequently involve the lumbar spine at the L4-L5 level.

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Background: Navigated instrumented spine surgery is burden by a low but significant screw mispositioning risks, respectively, for the 2D imaging system from 15% to 40% and, for the 3D imaging system, ranging from 4.1% to 11.5%.

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Purpose: To highlight a rare but potentially serious complication of frontal sinus injuries.

Patient: A case of delayed post-traumatic frontal sinus mucopyocoele presenting with meningitis in a 23-year-old male patient is reported.

Discussion: The anatomy of the frontal sinus is described in relation to the pathogenesis of muco(pyo)coele formation and the relevant literature is reviewed.

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