Publications by authors named "Masoud Neghab"

Unlabelled: This study was undertaken to ascertain whether long-term occupational exposure to inhalational anesthetic, was associated with any significant alteration in the parameters of immune function.

Materials And Methods: This was a historical cohort study in which 30 male participants with at least one year of work experience in the operating room at the time of the study and 30 unexposed referent subjects were investigated. Exposure levels were quantified by measuring the urinary concentrations of nitrous oxide (N2O), isoflurane, and sevoflurane gases by headspace gas chromatography-mass spectrometry.

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Cypermethrin, a member of the synthetic pyrethroids group, is a popular insecticide used to eliminate a broad range of common bugs in agricultural lands and households. However, studies of farmers' exposure to this insecticide are limited. The present study aimed to measure the respiratory exposure to cypermethrin among farmers and farm workers of Shiraz, as one of the biggest cities in Fars province, Iran.

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Article Synopsis
  • Workers in lead-zinc mines are exposed to lead dust, which can lead to serious health issues.
  • A study assessed the health impacts of low-level lead exposure on 73 mine workers compared to 70 non-exposed individuals, looking at blood samples and work conditions.
  • Results showed that while lead exposure levels were below safety limits, there were minor changes in some blood parameters among exposed workers, indicating potential health concerns that are not yet clinically significant.
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Exposure to inhalation anesthetics (IAs) has been associated with DNA damage as reflected in the increased frequency of micronuclei (MN) and chromosomal aberrations (CAs). The present study was undertaken to ascertain whether there was any correlation between increased MN and CA and the extent of oxidative stress as well as the antioxidant status of a group of operating room personnel exposed to a mixture of IAs, including nitrous oxide, isoflurane, and sevoflurane. In this cross-sectional study, 60 operating room personnel (exposed group) in whom the frequencies of MN and CA had already been shown to be significantly higher than those of a referent group, as well as 60 unexposed nurses, were studied.

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This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, including nitrous oxide, isoflurane, and sevoflurane was associated with any hepatotoxic or nephrotoxic changes. Fifty-two operating room personnel and 52 non-exposed subjects were studied. A questionnaire pertaining to demographic characteristics and medical history of participants was completed.

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This study aimed to assess respiratory symptoms and the pulmonary function test (PFT) in a group of poultry workers. The prevalence of respiratory symptoms was determined. Airborne concentrations of total and repairable dusts exceeded the threshold limit values.

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Background: Many workers, particularly those working in manufacture of fertilizers, explosives, rubber, pesticides, textiles, and employees of petrochemical industries are exposed to ammonia in their workplaces. Toxic responses of hematopoietic system and kidney following occupational exposure to this chemical have not been thoroughly investigated.

Objective: To determine the relationship between long-term occupational exposure to low levels of ammonia and hematological parameters and kidney function.

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Due to their wide applications, concern exists regarding possible genotoxic effects of inhalational anesthetics (IAs) among operating room personnel. This study was undertaken to examine genotoxic properties of co-exposure to nitrous oxide, sevoflurane, and isoflurane on induction of micronucleus (MN) and chromosomal aberrations (CAs) and to determine whether any associations exist between polymorphisms of GST genes and the level of genomic damage measured by MN and CAs assays. Sixty operating room personnel and 60 unexposed referent nurses were studied.

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This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, nitrous oxide, isoflurane, and sevoflurane was associated with any hematological changes. This historical cohort study was performed in 2018 at a large public hospital in Shiraz, where 52 operating room personnel and 52 administrative staff were investigated. The blood sample was taken from all individuals for Complete Blood Count.

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Background: Recently concern has been raised regarding possible health effects resulting from exposure of a group of pesticide retailers to chemicals they handle.

Objective: To investigate the prevalence of respiratory and dermal symptoms, as well as biomarkers of oxidative stress, among pesticide retailers and to compare them with those of an unexposed comparison group.

Methods: 70 male pesticide retailers and 64 male construction workers (served as the comparison group) were investigated.

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Objectives: The possible adverse respiratory effects of airborne pollutants in sawmills have not been thoroughly investigated in Iran. Additionally, the extent to which workers are exposed to this organic dust and its associated bioaerosols has not been extensively quantified. Likewise, the predominant bacterial and fungal species associated with wood dust have not been characterized.

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Respiratory effects of long term exposure to low levels of ammonia have not been thoroughly investigated. In this cross sectional study, 124 male subjects (67 high exposed and 57 low exposed), occupationally exposed to low levels of ammonia and 120 male referent individuals were investigated. Airborne concentrations of ammonia were measured and subjects underwent spirometry tests prior to and at end of their daily work shift.

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Objective: The aim of this study was to ascertain whether genetic polymorphism affects susceptibility of individuals to nephrotoxic potentials of benzene, toluene, ethyl-benzene, and xylenes (BTEXs).

Methods: Fifty BTEXs exposed workers with one or more abnormal parameter of kidney function and 232 referent subjects, with similar exposure history, free from any abnormal kidney parameters were investigated. Atmospheric concentrations of BTEXs were measured.

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Aims: This study was undertaken to ascertain whether light occupational exposure to pesticides by retailers might be associated with any liver, kidney, nervous system dysfunction or hematological abnormalities.

Main Methods: In this cross-sectional study, 70 male pesticide retailers (cases) and 64 male subjects, randomly selected from the constructions workers of city council contractors, as the referent group, were investigated. Urine and blood samples were taken from all subjects for urine analysis, hematological and biochemical parameters.

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Introduction: Occupational exposure to extremely low frequency magnetic fields (ELF-MF) occurs in many occupations such as welders, electric utility workers, train drivers and sewing machine operators. There is some evidence suggesting ELF-MF exposure to be a risk factor for Alzheimer's disease (AD). The current study aims at systematically reviewing the literature and conducting a meta-analysis to evaluate the risk of AD amongst workers exposed to ELF-MF.

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Occupational exposure to benzene has been associated with leukemia, anemia, leukopenia, and thrombocytopenia. Genetic susceptibility to benzene toxicity in humans may be related to variations in benzene metabolizing genes. The main objective of this study was to ascertain whether polymorphism of GSTP1, GSTM1, GSTT1 and CYP2E1 genes might influence susceptibility to the adverse effects of benzene among employees of a petrochemical plant.

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Background: Being exposed to cooking fumes, kitchen workers are occupationally at risk of multiple respiratory hazards. No conclusive evidence exists as to whether occupational exposure to these fumes is associated with acute and chronic pulmonary effects and symptoms of respiratory diseases.

Objective: To quantify the exposure levels and evaluate possible chronic and acute pulmonary effects associated with exposure to cooking fumes.

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Background: The present study was undertaken to ascertain whether (or not) long term occupational exposure to low (sub-TLV levels) atmospheric concentrations of chlorine gas was associated with any significant decrements in the parameters of pulmonary function and/or  increased prevalence of respiratory symptoms.

Methods: In this retrospective cohort study that was performed in 2012, 54 workers of a local chloralkali unit and 38 non-exposed office staff were enrolled and compared. Atmospheric concentrations of chlorine gas were measured by numerous sampling with gas detector tubes.

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Background: Unleaded petrol contains significant amounts of monocyclic aromatic hydrocarbons such as benzene, toluene, and xylenes (BTX). Toxic responses following occupational exposure to unleaded petrol have been evaluated only in limited studies. The main purpose of this study was to ascertain whether (or not) exposure to unleaded petrol, under normal working conditions, is associated with any hepatotoxic or nephrotoxic response.

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Objective: To investigate the prevalence of fecundity and other reproductive problems among a group of farmers in Kavar district of Fars province, southern Iran.

Methods: A total of 268 randomly selected married male farm workers were investigated. A questionnaire was devised and validated [Cronbach's α-coefficient (0.

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In this study, a miniature stirred tank bioreactor was designed for treatment of waste gas containing benzene, toluene and xylene. Oxygen mass transfer characteristics for various twin and single-impeller systems were investigated for 6 configurations in a vessel with 10 cm of inner diameter and working volume of 1.77L.

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The present study examined the biodegradation rate of benzene vapors in a two phase stirred tank bioreactor by a bacterial consortium obtained from wastewater of an oil industry refinery house. Initially, the ability of the microbial consortium for degrading benzene was evaluated before running the bioreactor. The gaseous samples from inlet and outlet of bioreactor were directly injected into a gas chromatograph to determine benzene concentrations.

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Introduction: The main purpose of this study was to investigate the respiratory effects of exposure to high airborne concentrations of wheat flour dust.

Methods: This cross-sectional study was carried out at a local wheat flour mill in Shiraz, southern Iran. Thirty-five male workers exposed to flour dust and 32 healthy male nonexposed employees were investigated.

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Synopsis of recent research by authors named "Masoud Neghab"

  • - Masoud Neghab's research primarily focuses on the health effects of occupational exposure to various harmful substances, including anesthetic gases and pesticides, emphasizing immunotoxicity and genotoxicity in workplace environments.
  • - His studies highlight significant health risks among different worker populations, such as elevated immune dysfunction in operating room personnel and respiratory issues in agricultural workers, linking these effects to chronic exposure to toxic substances like nitrous oxide and cypermethrin.
  • - Neghab's work also investigates the relationship between genetic factors and the genotoxic effects of inhalational anesthetics, contributing to a deeper understanding of the biological consequences of occupational exposures on hematological and kidney health.