A Novel Curvature-Based Algorithm for Automatic Grading of Retinal Blood Vessel Tortuosity.

Tortuosity of retinal blood vessels is an important symptom of diabetic retinopathy or retinopathy of prematurity. In this paper, we propose an automatic image-based method for measuring single vessel and vessel network tortuosity of these vessels. Simplicity of the algorithm, low-computational burden, and an excellent matching to the clinically perceived tortuosity are the important features of the proposed algorithm.