Neuroprotective role of chrysin in attenuating loss of dopaminergic neurons and improving motor, learning and memory functions in rats.

Objective: Selective degeneration of dopaminergic neurons is the pathological hallmark of Parkinson disease (PD). Enhanced oxidative stress, lipid peroxidation and susceptibility of dopaminergic neurons to apoptotic cellular death are the leading pathogenetic mechanisms. Chrysin is an active flavonoid.

Prevalence and trends of overweight and obesity amongst Saudi school children, a study done by using three noninvasive methods.

Unlabelled: Obesity has become a global epidemic. It's level in the Middle Eastern and Asian countries have reached to an alarming level. Rapid transition of life style and urbanization has not only affected adults but also the younger population.

Growth plate changes associated with Hypothyroidism amongst the pre and postnatal rats.

Objectives: This study is intended to examine the effect of hypothyroidism and thyroxin replacement on axial and appendicular skeletal growth, growth plate thickness and to observe associated microscopic changes within the growth plates.

Methodology: Experimental albino rats were developed with carbimazole and carbimazole plus thyroxin. Animals were administered with these drugs throughout pregnancy (prenatally) and for a period of six weeks, postnatally.

Ultra structural evidence of axonal regeneration following intracranial transection of optic nerve.

Objective: The present work was aimed at studying the ultra structural changes of the proximal (retinal) stump of the intracranially transected optic nerve of the rat for any possible regenerative ability.

Methods: Specimens were collected one (1 wpo) and four weeks(4 wpo) after the transection and the cross sections of the stumps were studied by electron microscopy by dividing them into three zones, (1) the central zone, (2) the intermediate zone, and (3) the peripheral zone.

Results: The present results showed evident morphological changes in these zones both in the 1 wpo and 4 wpo groups.