Publications by authors named "Mason R Kolanowski"
Article Synopsis
- Parkinson's disease (PD) is rapidly increasing globally, especially in industrialized regions, indicating potential environmental influences, specifically from pollutants like dieldrin, a pesticide.
- Research on mice reveals that exposure to dieldrin during development makes them more vulnerable to neuron damage and motor function deficits when exposed to α-synuclein, a protein linked to PD.
- The study shows that while dieldrin exposure increases dopamine release in certain brain areas affected by α-synuclein, it doesn't change VMAT2 activity, suggesting that early exposure to dieldrin may heighten the brain's response to neurodegeneration without obvious signs of damage.
