Publications by authors named "Mason A Shipley"
Article Synopsis
- - After HSV-1 virus enters host cells, its genome quickly becomes heterochromatinized, limiting viral gene expression, but it needs to de-repress this chromatin for effective replication.
- - The HSV-1 genome has encoded CTCF insulators that are crucial for regulating the transcription of immediate early (IE) genes throughout the virus's life cycle, with a specific focus on the CTRL2 insulator linked to gene silencing during latency.
- - Research using a recombinant virus lacking the CTRL2 insulator revealed that this absence led to reduced gene expression and replication defects, as increased repressive histone markers around the IE gene regions hindered chromatin accessibility during early infection stages.
It has been 49 years since the last discovery of a new virus family in the model yeast Saccharomyces cerevisiae. A large-scale screen to determine the diversity of double-stranded RNA (dsRNA) viruses in S. cerevisiae has identified multiple novel viruses from the family Partitiviridae that have been previously shown to infect plants, fungi, protozoans, and insects.
View Article and Find Full Text PDFCompared to other species of yeasts, the growth of Candida glabrata is inhibited by many different strains of killer yeasts. The ionophoric K1 and K2 killer toxins are broadly inhibitory to all clinical isolates of C. glabrata from patients with recurrent vulvovaginal candidiasis, despite high levels of resistance to clinically relevant antifungal therapeutics.
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