Publications by authors named "Maslyn Ann Greene"
Article Synopsis
- TGFβ-activated kinase-1 (TAK1) plays a role in both muscle growth (hypertrophy) and muscle loss (wasting), indicating its complex function in muscle health.
- A study investigated how TAK1's phosphorylation affects different muscle models, showing varying phosphorylation patterns in Texel sheep (muscle growth) and cancer-induced cachexia (muscle loss), specifically noting differences in proteins like p38, p90RSK, and HSP27.
- In C2C12 muscle cells, reduced TAK1 phosphorylation initially promotes muscle growth but prolonged inhibition leads to muscle failure, highlighting the importance of timing in TAK1 activation for regulating muscle-related processes.
