[Injuries of the cranio-cervical junction--anatomy, classification of pathological process, and diagnosis].

The cranio-atlanto-axial junction (C0-C2) is anatomically and biomechanically the most complex spinal region. It is frequently engaged by different pathologies of tumoral, traumatical or inflammatory origin, leading to spinal instability. The advanced knowledge about the anatomical details, the physiology, the mechanism of injury, the nature of the processes and their classification are crucial for the adequate therapeutic approach when dealing with pathologies in this region.

[Quality of life assessment in patients with malignant glial tumors].

Introduction: High-grade gliomas are the most common primary brain tumors. Dismal prognosis for the patients with a marked deterioration of the quality of life and a mean length of survival of 9-18 months are typical characteristics for this pathology. The aim of this study is to assess the most appropriate questionnaire for measuring the quality of life (QOL) in this group of patients.

Effect of dotarizine on K(+)-stimulated [3H]-serotonin and [3H]-acetylcholine release from rat hippocampus.

1. The effect of the diphenylmethyl-piperazine derivative dotarizine on K(+)-stimulated release of [3H]serotonin ([3H]5-HT) and [3H]acethylcholine ([3H]Ach) in rat hippocampal slices was studied. 2.