Genome-wide association study on chronic postsurgical pain after abdominal surgeries in the UK Biobank.

Introduction: Chronic pain is one of the most common and severe complications after surgery, affecting quality of life and overall wellbeing of patients. Several risk factors have been identified but the mechanisms of chronic postsurgical pain development remain unclear. This study aimed to identify single-nucleotide polymorphisms associated with developing chronic postsurgical pain after abdominal surgery, one of the most common types of surgery.

[Adhesions after abdominal surgery: developments in diagnosis and treatment].

Adhesions are a form of internal scar tissue, that develops in 70-90% of patients undergoing abdominal surgery. Although most adhesions are asymptomatic, adhesions cause a lifelong risk for complications, including adhesive small bowel obstruction (ASBO), chronic pain, infertility and difficulties during reoperations. ASBO is an abdominal emergency, resulting in hospital readmissions and a reoperation in 30-50% of cases.

Predicting long-term risk of reoperations following abdominal and pelvic surgery: a nationwide retrospective cohort study.

Background: The risk of reoperations after abdominal and pelvic surgery is multifactorial and difficult to predict. The risk of reoperation is frequently underestimated by surgeons as most reoperations are not related to the initial procedure and diagnosis. During reoperation, adhesiolysis is often required, and patients have an increased risk of complications.

Risk Factors for Adhesion-Related Readmission and Abdominal Reoperation after Gynecological Surgery: A Nationwide Cohort Study.

More than half of women in developed countries undergo surgery during their lifetime, putting them at risk of adhesion-related complications. Adhesion-related complications include small bowel obstruction, chronic (pelvic) pain, subfertility, and complications associated with adhesiolysis during reoperation. The aim of this study is to predict the risk for adhesion-related readmission and reoperation after gynecological surgery.

Elective adhesiolysis for chronic abdominal pain reduces long-term risk of adhesive small bowel obstruction.

Background: Selected patients with adhesion-related chronic abdominal pain can be treated effectively by adhesiolysis with the application of adhesion barriers. These patients might also have an increased risk to develop adhesive small bowel obstruction (ASBO). It is unknown how frequently these patients develop ASBO, and how elective adhesiolysis for pain impacts the risk of ASBO.

Predicting the outcome of closed-loop small bowel obstruction by preoperative characteristics.

Background: Closed-loop small bowel obstruction (CL-SBO) can threaten the viability of the intestine by obstructing a bowel segment at two adjacent points. Prompt recognition and surgery are crucial.

Aim: To analyze the outcomes of patients who underwent surgery for CL-SBO and to evaluate clinical predictors.

[Transpapillary gallbladder drainage with 'pigtail' stent].

The transpapillary double 'pigtail' stent is placed endoscopically to drain the gallbladder after remission of a (recurrent) acute cholecystitis in patients with increased surgical risk. Technical success rate (placement of stent) is 83-88% and clinical success rate (remission of symptoms) is 80-93%. Although the procedure is effective, the stent is not commonly implemented.

Correlation of CT findings with intra-operative outcome in closed-loop small bowel obstruction (CL-SBO).

Purpose: To correlate CT-findings in patients with closed-loop small bowel obstruction (CL-SBO) with perioperative findings, to identify patients who require immediate surgical intervention. Secondary purpose was to substantiate the role of radiologists in predicting perioperative outcome.

Methods: Data were retrospectively obtained from patients with surgically confirmed CL-SBO, between September 2013 and September 2019.