Attribution of fine particulate matter and ozone health impacts in Canada to domestic and US emission sources.

Exposure to ambient air pollution is associated with a wide range of adverse health effects such as respiratory symptoms, cardiovascular events, and premature mortality. Canada and the United States (US) have worked collaboratively for decades to address transboundary air pollution and its impacts across their shared border. To inform transboundary air quality considerations, we conducted modelling to attribute health impacts from ambient PM and O exposure in Canada to Canadian and US emission sources.

The HTAP_v3 emission mosaic: merging regional and global monthly emissions (2000-2018) to support air quality modelling and policies.

This study, performed under the umbrella of the Task Force on Hemispheric Transport of Air Pollution (TF-HTAP), responds to the global and regional atmospheric modelling community's need of a mosaic emission inventory of air pollutants that conforms to specific requirements: global coverage, long time series, spatially distributed emissions with high time resolution, and a high sectoral resolution. The mosaic approach of integrating official regional emission inventories based on locally reported data, with a global inventory based on a globally consistent methodology, allows modellers to perform simulations of high scientific quality while also ensuring that the results remain relevant to policymakers. HTAP_v3, an ad hoc global mosaic of anthropogenic inventories, has been developed by integrating official inventories over specific areas (North America, Europe, Asia including Japan and South Korea) with the independent Emissions Database for Global Atmospheric Research (EDGAR) inventory for the remaining world regions.

The efficacy of cognitive-motor rehabilitation on cognitive functions and behavioral symptoms of attention deficit/hyperactivity disorder (ADHD) children: Specification of near-transfer and far-transfer effects in comparison to medication.

Background And Aim: This study aimed to investigate and compare the efficacy of cognitive-motor rehabilitation (CMR) with methylphenidate on cognitive functions and behavioral symptoms of children with attention deficit/hyperactivity disorder (ADHD) and specified the near-transfer and far-transfer effects.

Materials And Methods: The research was semiexperimental with posttest and follow-up assessments, in a single-blind design. Forty-eight boys with ADHD, aged 9-12, were selected conveniently regarding the inclusion/exclusion criteria, matched base on severity and Intelligence quotient (IQ) and were randomly assigned to CMR ( = 16), methylphenidate medication (MED, = 16), and placebo CMR groups (PCMR, = 16).

The Diagnostic Accuracy of Galectin-9 for Diagnosis of Endometriosis in Comparison with Laparoscopy.

Background: Endometriosis is a common devastating gynecological disease with severe complications. Researches on noninvasive diagnostic tests with acceptable accuracy are still ongoing. The purpose of the present study was to evaluate the diagnostic value of serum Galectin-9 (Gal-9) level in comparison with laparoscopic results in endometriosis patients.

Association of Absent or Trace Fluid in the Maxillary Sinus and Inferior Rectus Muscle Entrapment in Patients With Orbital Floor Fracture.

Inferior rectus (IR) entrapment requires urgent surgical intervention in patients with traumatic orbital floor fracture (OFF). We evaluated 47 patients who underwent CT showing acute OFF, 10 of whom had surgically confirmed entrapment. Absent or trace dependent fluid in the ipsilateral maxillary sinus had sensitivity of 40% and specificity of 95% for entrapment.

Evaluation of Multiple Semi-Twisted Tape Inserts in a Heat Exchanger Pipe Using AlO Nanofluid.

The hydrothermal performance of multiple semi-twisted tape inserts inside a heat exchanger pipe is numerically examined in three-dimensions. This study aims to find the optimum case for having the highest heat transfer enhancement with the lowest friction factor using nanofluid (AlO/water). A performance evaluation criterion (PEC) is defined to characterize the performance based on both friction factor and heat transfer.

Isolating the impact of COVID-19 lockdown measures on urban air quality in Canada.

Unlabelled: We have investigated the impact of reduced emissions due to COVID-19 lockdown measures in spring 2020 on air quality in Canada's four largest cities: Toronto, Montreal, Vancouver, and Calgary. Observed daily concentrations of NO, PM, and O during a "pre-lockdown" period (15 February-14 March 2020) and a "lockdown" period (22 March-2 May 2020), when lockdown measures were in full force everywhere in Canada, were compared to the same periods in the previous decade (2010-2019). Higher-than-usual seasonal declines in mean daily NO were observed for the pre-lockdown to lockdown periods in 2020.

Investigation of Overlapped Twisted Tapes Inserted in a Double-Pipe Heat Exchanger Using Two-Phase Nanofluid.

This study investigated the laminar convective heat transfer and fluid flow of AlO nanofluid in a counter flow double-pipe heat exchanger equipped with overlapped twisted tape inserts in both inner and outer tubes. Two models of the same (co-swirling twisted tapes) and opposite (counter-swirling twisted tapes) angular directions for the stationary twisted tapes were considered. The computational fluid dynamic simulations were conducted through varying the design parameters, including the angular direction of twisted tape inserts, nanofluid volume concentration, and Reynolds number.

Radiomic features of the pancreas on CT imaging accurately differentiate functional abdominal pain, recurrent acute pancreatitis, and chronic pancreatitis.

Purpose: Patients with recurrent abdominal pain and pancreatic enzyme elevations may be diagnosed clinically with recurrent acute pancreatitis (RAP) even with normal imaging or no imaging at all. Since neither abdominal pain nor enzyme elevations are specific for acute pancreatitis (AP), and patients with RAP often have a normal appearing pancreas on CT after resolution of an AP episode, RAP diagnosis can be challenging. This study aims to determine if quantitative radiomic features of the pancreas on CT can differentiate patients with functional abdominal pain, RAP, and chronic pancreatitis (CP).

Gastric atrophy: use of OLGA staging system in practice.

Aim: This study used the OLGA system to characterize the histology pattern of gastritis in dyspeptic outpatients with a mean age of 45 years from regions with different gastric cancer risks.

Background: Several classification systems have been purposed for understanding the status of the gastric mucosa. Currently, the Sydney system is the most widely employed.

Analytical development and optimization of a graphene-solution interface capacitance model.

Graphene, which as a new carbon material shows great potential for a range of applications because of its exceptional electronic and mechanical properties, becomes a matter of attention in these years. The use of graphene in nanoscale devices plays an important role in achieving more accurate and faster devices. Although there are lots of experimental studies in this area, there is a lack of analytical models.

In-vitro/In-vivo comparison of leuprolide acetate release from an in-situ forming plga system.

A poly (lactide-co-glycolide) (PLGA) implant was used to control the release profile of leuprolide acetate (LA) drug. The system is an in-situ polymeric precipitation system. And the formulation consisted of PLGA polymer, LA drug and N-methyl-2-pyrrolidon solvent with no additives.

Intestinal leishmaniasis in acquired immunodeficiency syndrome.

In endemic regions, visceral leishmaniasis is one of the most common opportunistic infections in HIV positive patients. Simultaneous infection with Leishmania and HIV has been reported in some countries but this is the first report of such a case in Iran. Our patient was a 27 years old man with intermittent night fever, abdominal pain, loss of appetite, vomiting, watery diarrhea and severe weight loss for 6 months.

G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition.

G protein-coupled receptor kinases (GRKs) phosphorylate activated G protein-coupled receptors, leading to their desensitization and endocytosis. GRKs have also been implicated in phosphorylating other classes of proteins and can localize in a variety of cellular compartments, including the nucleus. Here, we attempted to identify potential nuclear substrates for GRK5.

G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression.

G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptor function and mediate receptor desensitization, internalization, and signaling. While GRKs also interact with and/or phosphorylate many other proteins and modify their function, relatively little is known about the cellular localization of endogenous GRKs. Here we report that GRK5 co-localizes with γ-tubulin, centrin, and pericentrin in centrosomes.

Proinflammatory cytokines and thrombomodulin in patients with peptic ulcer disease and gastric cancer, infected with Helicobacter pylori.

Backgrounds: Helicobacter pylori infect more than half of the global population. It is suggested to be related with gastritis, peptic ulcer disease (PUD), and gastric cancer.

Aims: The aim of this present study was to evaluate proinflammatory cytokines including interleukin 1, 6, 8, 10, and thrombomodulin in H.

Clinical and histological presentation of Helicobacter pylori and gluten related gastroenteropathy.

Background: Celiac disease has been reported to be associated with gastric abnormalities. The aim of this study was to assess the relationship between the prevalence of celiac disease and Helicobacter pylori infection in an Iranian population of 250 patients.

Methods: Biopsies were taken from the gastric antrum and duodenum.

Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?

Background: The significance of expression of different mucins in succession of malignant transformation of colorectal polyps is not determined yet. The aim of the present study was to determine the pattern of expression of MUC1, MUC2, MUC5AC and MUC6 in colorectal polyps and to evaluate the applicability of using mucin expression in predicting the extent of malignant transformation in colorectal polyps.

Methods: A total of 454 polyp specimens comprising 36 hyperplastic polyps, 15 serrated adenomas, 258 tubular adenomas, 114 tubulovillous adenomas, and 31 villous adenomas were included in this study, and were immunostained for MUC1, MUC2, MUC5AC and MUC6 by using mucin specific antibodies.

CagA status and VacA subtypes of Helicobacter pylori in relation to histopathologic findings in Iranian population.

Background/objective: The aim of this study was to detect dominant cagA/vacA genotypes of Helicobacter Pylori (H. pylori) and determine correlations between different cagA/vacA genotypes and histologic features of chronic gastritis in Iranian patients.

Methods: Gastric biopsy was taken from 166 patients with nonulcer dyspepsia.