Publications by authors named "Masceline J Mutsaka-Makuvaza"

Schistosomiasis, a parasitic disease with a complex transmission mechanism, requiring a snail intermediate host, is influenced by biology, the environment, human behavior and the prevailing socioeconomic situation. This study aimed to systematically investigate the importance and feasibility of indicators related to the factors influencing transmission and intervention measures for and . Based on a literature review and group discussions according to the Delphi method, a framework questionnaire was designed.

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  • * The study was qualitative, involving 128 participants from diverse backgrounds, including religious leaders, health workers, and teachers, to explore their knowledge and beliefs about COVID-19 and misinformation.
  • * Despite the positive awareness, the presence of misinformation highlights the need for the Zimbabwean government to implement better systems for monitoring information and improving public communication about health measures.
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Zimbabwe, located in Southern Africa, faces a significant public health challenge due to schistosomiasis. We investigated this issue with emphasis on risk prediction of schistosomiasis for the entire population. To this end, we reviewed available data on schistosomiasis in Zimbabwe from a literature search covering the 1980-2022 period considering the potential impact of 26 environmental and socioeconomic variables obtained from public sources.

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Background: Vaccines are effective biological interventions that reduce health burdens. However, during the COVID-19 pandemic, there were concerns about varying levels of COVID-19 vaccination coverage in the Zimbabwean population. This study aimed to understand facilitators and barriers to COVID-19 vaccine uptake in the Zimbabwean population.

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Background: Practicing hand hygiene is recommended as one of the key preventive measures for reducing the transmission of COVID-19 and other infectious agents. However, it is often not practiced frequently enough or correctly by the public. We aimed to identify barriers to and facilitators of hand hygiene in the Zimbabwean population during the COVID-19 pandemic.

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  • This study investigates the relationship between religious affiliation and health outcomes among young people living with HIV (YPLHIV) in Zimbabwe, aiming to provide advanced statistical analysis rather than just descriptive data.
  • Data was collected from 804 YPLHIV (ages 14-24) to assess their beliefs about HIV, health-seeking behaviors, viral loads, opportunistic infections, and mental health, using multilevel mixed-effects logistic regression for analysis.
  • Results indicate that traditional religious affiliation is associated with lower viral loads, while certain perceptions of HIV and objections to therapies can lead to higher risks of treatment failure and opportunistic infections, highlighting the significant influence of religion on health outcomes in this population.
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Introduction: The role of religion and spirituality as social determinants of health has been widely discussed. Studies among people living with HIV describe positive and negative influences of religion and spirituality on health outcomes. With a HIV prevalence of 14.

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  • This study aimed to validate the Religious and Spiritual Struggles scale (RSS) in Zimbabwe, specifically for young people living with HIV (YPLHIV) aged 14-24, as most validations have occurred in high-income settings.
  • Researchers collected data from 804 respondents in 2021 using an Open Data Kit questionnaire and employed various statistical analyses, including exploratory factor analysis (EFA), due to low confirmability of the original scale's sub-dimensions.
  • The EFA revealed four new, culturally relevant sub-domains linked to health, supporting the validity of the RSS in this context, while also suggesting the need for further validation with diverse populations in sub-Saharan Africa.
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  • * It highlights the use of empirical data from local prevalence testing and digital environmental imagery to inform mapping efforts, especially in areas lacking comprehensive disease registries.
  • * Through case studies on soil-transmitted helminths in Kenya, Sierra Leone, and Zimbabwe, the article demonstrates that model-based geostatistics significantly outperforms current WHO guidelines in designing and analyzing prevalence surveys, indicating potential for improved mapping in other diseases.
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This paper reports the prevalence and intensity of soil-transmitted helminth (STH) infections measured in Zimbabwe before and after a control intervention based on annual deworming of school-age children (SAC) conducted from 2012 to 2018. In 2010, epidemiological data were collected from 13 195 SAC in 255 randomly selected schools in all districts nationwide using, as diagnostic methods, the Kato-Katz and the formal ether stool concentration technique. At follow up, conducted in 2017, only Kato-Katz was performed; specimens were collected from 13 352 children in 336 schools.

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Background: Treatment needs for Schistosoma haematobium are commonly evaluated using urine filtration with detection of parasite eggs under a microscope. A common symptom of S. haematobium is hematuria, the passing of blood in urine.

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The fresh water snail Biomphalaria pfeifferi is the intermediate host for Schistosoma mansoni, which causes human intestinal schistosomiasis in Zimbabwe. Despite the medical importance of this intermediate host, there are no current data on its molecular characterization in Zimbabwe. In 2016, human water contact sites were identified in four communities in Madziwa area, Shamva district, Zimbabwe.

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  • The study investigates the genetic diversity and evolutionary history of Bulinus snails, which are key vectors for the Schistosoma haematobium parasite responsible for urogenital schistosomiasis in Zimbabwe.
  • Researchers collected 1,570 Bulinus snails over a year, finding that only 1.9% of B. globosus were infected, while B. truncatus showed no infections; genetic analysis revealed diverse populations within both species.
  • Results indicate a low prevalence of schistosome infection among the snails, suggesting limited transmission potential in the Madziwa region and contributing to the understanding of these snail species' dynamics.
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  • Schistosomiasis predominantly impacts underprivileged communities lacking access to clean water and sanitation, leading to the study aimed at understanding women's knowledge and practices regarding the disease in rural Zimbabwe.
  • A survey with 426 women revealed that while the majority were aware of schistosomiasis and its transmission, certain socio-demographic factors, such as age and education level, influenced their understanding and behaviors related to the disease.
  • Findings indicated that older women were more aware of infertility risks, while women with prior infections felt a stronger belief in current infection; additionally, uneducated women and non-apostolic followers had riskier water-related practices.
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  • The study investigated the prevalence of urogenital schistosomiasis among preschool-aged children and their caregivers in Zimbabwe, finding that 15.4% of participants were infected, with a higher prevalence among caregivers (18.7%) than children (13.3%).
  • Key risk factors for infection included the use of river water for bathing, which significantly increased infection rates for both children and their caregivers.
  • The research highlights the importance of understanding disease profiles and risk factors to design effective control programs targeting both women and young children in endemic areas.
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The transmission of some schistosome parasites is dependent on the planorbid snail hosts. is important in urinary schistosomiasis epidemiology in Africa. Hence, there is a need to define the snails' phylogeography.

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Background: In light of the shift to aiming for schistosomiasis elimination, the following are needed: data on reinfection patterns, participation, and sample submission adherence of all high-risk age groups to intervention strategies. This study was conducted to assess prevalence, reinfections along with consecutive participation, sample submission adherence, and effect of treatment on schistosomiasis prevalence in children aged five years and below in an endemic district in Zimbabwe, over one year.

Methods: The study was conducted from February 2016-February 2017 in Madziwa area, Shamva district.

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Background: Recent research has shown that in schistosome-endemic areas preschool-aged children (PSAC), that is, ≤5 years, are at risk of infection. However, there exists a knowledge gap on the dynamics of infection and morbidity in this age group. In this study, we determined the incidence and dynamics of the first urogenital schistosome infections, morbidity and treatment in PSAC.

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Background: Reliable mapping of soil-transmitted helminth (STH) parasites requires rigorous statistical and machine learning algorithms capable of integrating the combined influence of several determinants to predict distributions. This study tested whether combining edaphic predictors with relevant environmental predictors improves model performance when predicting the distribution of STH, Ascaris lumbricoides and hookworms at a national scale in Zimbabwe.

Methods: Geo-referenced parasitological data obtained from a 2010/2011 national survey indicating a confirmed presence or absence of STH among school children aged 10-15 years was used to calibrate ten species distribution models (SDMs).

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