Impairment of Trk-neurotrophin receptor by the serum of a patient with subacute sensory neuropathy.

Background: Paraneoplastic peripheral neuropathy is sometimes associated with unidentified neuronal autoantibodies.

Objective: To examine the effects of serum from a patient with subacute sensory axonopathy on the function of the Trk high-affinity nerve growth factor receptor.

Patient: An 86-year-old man with sensory neuropathy exhibiting an autoantibody to Trk.

Neurologic complications associated with influenza vaccination: two adult cases.

We describe two adult cases of neurologic complications occurring after influenza vaccination. The first case was a 62-year-old man who experienced convulsions 5 days after vaccination, and the second case was a 70-year-old man who exhibited paraplegia 7 days after vaccination. Diagnoses of acute disseminated encephalomyelitis and transverse myelitis with acute motor axonal neuropathy were made, respectively, and steroid pulse therapy and intravenous gamma globulin therapy alleviated the patients' symptoms.