Publications by authors named "Masayuki Okabe"

An 82-year-old woman, who underwent a mastectomy for right breast cancer 35 years ago, presented to our hospital with a chief complaint of general malaise and dyspnea. A chest CT scan revealed a right pleural effusion and multiple bone metastases. Upper gastrointestinal endoscopy revealed a small bulge in the mid gastric fold, which was diagnosed as a metastatic breast cancer lesion, based on pathological diagnosis and immunostaining findings.

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Pancreatic cancer(PC)is associated with poor prognosis and low resectability rates. Currently, only 15-20% of all patients are candidates for upfront surgery at the time of diagnosis, which offers the chance of long-term survival. In recent years, patients with borderline resectable PC(BR-PC)have been treated with surgery following neoadjuvant chemoradiotherapy or intensive multi-agent chemotherapy.

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A 54-year-old male patient with a chief complaint of right lower abdominal pain and nausea visited the reporting hospital. Abdominal computed tomography was performed, which showed findings of a membrane-covered internally heterogeneous solid mass associated with a 11×10 cm well-circumscribed calcification, as well as ileus in the right lower abdomen. Based on the imaging findings, it was diagnosed with liposarcoma, and surgery was performed for both diagnosis and treatment.

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We report a case of a 63-year-old man with a perirectal abscess due to rectal cancer referred to us from another clinic. We performed 3 courses of preoperative chemotherapy using mFOLFOX6 and then performed a Miles operation plus D3 dissection followed by reconstruction of an artificial anus using the ileum. The pathological diagnosis was tub2, pAI(prostate), pN0 (0/12), ND(v+), and fStage Ⅲa.

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A 69-year-old woman underwent extended cholecystectomy for gallbladder cancer[T2N0M0, fStage Ⅱ(UICC 7th edition)]. She was then administered adjuvant S-1 and was treated for drug-induced neutropenia. One year later, recurrent lesions were detected in liver S4 and S5.

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Article Synopsis
  • The management of simultaneous liver metastasis from colorectal cancer (SCRLM) is debated, with hepatic metastasectomy being the preferred option when feasible.
  • Radiofrequency ablation (RFA) serves as a less invasive alternative for patients unwilling or unsuitable for surgery or long-term chemotherapy.
  • This report discusses two cases where surgery was combined with RFA and adjuvant chemotherapy, suggesting a potential approach for achieving local control of liver metastases in select patients.
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Article Synopsis
  • Amyand's hernia occurs when the appendix is found within an inguinal hernia sac, typically going undiagnosed before surgery.
  • A case involving a 76-year-old man showed preoperative detection of this condition through imaging, leading to a combined laparoscopic repair and appendectomy.
  • The study suggests that laparoscopic techniques for both repairing the hernia and removing the appendix are effective and safe, with good patient outcomes.
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BACKGROUND Intimal sarcoma (IS) is a malignant mesenchymal tumor with predominantly intraluminal growth in large vessels and the heart. Due to the rarity of cases it often poses diagnostic problems in clinical and pathological settings. Although the classification of IS is still controversial, undifferentiated type of IS has recently been found to show immunohistochemical positivity with MDM2, CDK4, or PDGFRA and amplification of MDM2/CDK4 and PDGFRA.

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This article proposes a constrained clustering algorithm with competitive performance and less computation time to the state-of-the-art methods, which consists of a constrained k-means algorithm enhanced by the boosting principle. Constrained k-means clustering using constraints as background knowledge, although easy to implement and quick, has insufficient performance compared with metric learning-based methods. Since it simply adds a function into the data assignment process of the k-means algorithm to check for constraint violations, it often exploits only a small number of constraints.

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We report a rare case of ectopic pancreatic cancer in the mesentery of the jejunum. A 68-year-old man presented with left abdominal pain. Contrast-enhanced abdominal CT revealed a 3-cm tumor in the mesentery near the ligament of Treitz.

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