Chiral Induction of a Tetrakis(porphyrin) in Various Chiral Solvents.

Non-covalent interactions offer an alternative way for developing stimulus-responsive materials such as sensors, machines, and drug-delivery systems. We recently reported that a urethane-equipped tetrakis(porphyrin) forms one-handed helical supramolecular polymers in solution in response to chirality of chiral solvents. Conformational changes in helical sense were detected using circular dichroism (CD) spectroscopy, which showed that the tetrakis(porphyrin) can possibly be used as a sensor for determining the enantiomeric excess of a chiral analyte.

Controlled Helical Organization in Supramolecular Polymers of Pseudo-Macrocyclic Tetrakisporphyrins.

Tetrakisporphyrin monomers with amino acid side chains at each end form intramolecular antiparallel hydrogen-bonds to adopt chirally twisted pseudo-macrocyclic structures that result in right-handed and left-handed (P)- and (M)-conformations. The pseudo-macrocyclic tetrakisporphyrin monomers self-assembled to form supramolecular helical pseudo-polycatenane polymers via head-to-head complementary dimerization of the bisporphyrin cleft units in an isodesmic manner. The formation of one-handed supramolecular helical pseudo-polycatenane polymers was confirmed by circular dichroism (CD) spectroscopy.

Incremental structure building in the processing of ellipsis.

This article presents the results of two experiments conducted to examine how ellipsis sites are processed during the processing of backward sluicing, which is superficially similar to non-sluicing wh-filler-gap dependencies. Previous studies on long-distance wh-filler-gap dependencies established that the processing of these dependencies is sensitive to the syntactic structure of materials within the dependency: CP vs. NP.

Processing wh-filler-gap dependencies.

We present experimental evidence showing that different wh-filler-gap dependencies are processed differently, depending on their syntactic licensors. Our studies compared the active storage profiles for , , and (serving as subject or object of the verb). The results of offline and online experiments revealed that these wh-fillers are stored in memory for different durations, and predictably so based on the hypothesised structural distance between each wh-filler and the licensor which determines its grammatical and interpretive functions.

The role of category ambiguity in normal and impaired lexical processing: can you without the ?

Introduction: Many words are categorially ambiguous and can be used as a verb () or as a noun () due to the presence of unpronounced morphology or "zero morphology". On this account, the verb "paint" is derived from the noun "paint" through the addition of a silent category-changing morpheme. Past studies have uncovered the syntactic and semantic properties of these categorially ambiguous words, but no research has been conducted on how people process them during normal or impaired lexical processing.

A Case of Chronic Active Antibody-Mediated Rejection Caused by a Pre-Existing Anti-DQ Donor-Specific Antibody in a Systemic Lupus Erythematosus Recipient Without History of Sensitization: A Case Report.

Background: Systemic lupus erythematosus (SLE) is reported to produce anti-HLA antibodies. We report a case of chronic active antibody-mediated rejection caused by pre-existing donor-specific antibody (DSA) in a patient with SLE without a history of sensitization.

Case Report: The case was a 29-year-old man with end-stage renal disease due to lupus nephritis.

Self-assembly of neutral platinum complexes controlled by thermal inputs.

In this report, we describe the self-assembly behavior of neutral platinum complexes in toluene. The platinum complexes were seen to form two different types of assemblies depending on the preparation temperature.

Negative polarity item (NPI) illusion is a quantification phenomenon.

Illusions of grammaticality have often been used to probe the properties of the human sentence processor in syntactic activities like subject-verb agreement, reflexive binding, and negative polarity item (NPI) licensing. Originally, NPI licensing in processing was thought to be a product of cue-based retrieval. Mounting evidence that the NPI illusion is far from universal suggests that a revised account is necessary.

Self-assembly of neutral platinum complexes possessing chiral hydrophilic TEG chains.

Neutral platinum complexes that possess chiral triethylene glycol (TEG) moieties were synthesized. The platinum complexes formed helically twisted stacked assemblies in chloroform and toluene, which were studied by H NMR, UV/vis spectroscopy, and emission spectroscopy. On the other hand, emissive micellar aggregates were observed in a THF/water mixed solvent.

Processing gapping: Parallelism and grammatical constraints.

This study aims to test two hypotheses about the online processing of Gapping: whether the parser inserts an ellipsis site in an incremental fashion in certain coordinated structures (the Incremental Ellipsis Hypothesis), or whether ellipsis is a late and dispreferred option (the Ellipsis as a Last Resort Hypothesis). We employ two offline acceptability rating experiments and a sentence fragment completion experiment to investigate to what extent the distribution of Gapping is controlled by grammatical and extra-grammatical constraints. Furthermore, an eye-tracking while reading experiment demonstrated that the parser inserts an ellipsis site incrementally but only when grammatical and extra-grammatical constraints allow for the insertion of the ellipsis site.

Wh-filler-gap dependency formation guides reflexive antecedent search.

Prior studies on online sentence processing have shown that the parser can resolve non-local dependencies rapidly and accurately. This study investigates the interaction between the processing of two such non-local dependencies: wh-filler-gap dependencies (WhFGD) and reflexive-antecedent dependencies. We show that reflexive-antecedent dependency resolution is sensitive to the presence of a WhFGD, and argue that the filler-gap dependency established by WhFGD resolution is selected online as the antecedent of a reflexive dependency.

Grammatical Planning Units During Real-Time Sentence Production in Speakers With Agrammatic Aphasia and Healthy Speakers.

Purpose: Grammatical encoding (GE) is impaired in agrammatic aphasia; however, the nature of such deficits remains unclear. We examined grammatical planning units during real-time sentence production in speakers with agrammatic aphasia and control speakers, testing two competing models of GE. We queried whether speakers with agrammatic aphasia produce sentences word by word without advanced planning or whether hierarchical syntactic structure (i.

Parallel functional category deficits in clauses and nominal phrases: The case of English agrammatism.

Individuals with agrammatic aphasia exhibit restricted patterns of impairment of functional morphemes, however, syntactic characterization of the impairment is controversial. Previous studies have focused on functional morphology in clauses only. This study extends the empirical domain by testing functional morphemes in English nominal phrases in aphasia and comparing patients' impairment to their impairment of functional morphemes in English clauses.

Expression profiles and physiological roles of two types of molecular chaperonins from the hyperthermophilic archaeon Thermococcus kodakarensis.

Thermococcus kodakarensis possesses two chaperonins, CpkA and CpkB, and their expression is induced by the downshift and upshift, respectively, of the cell cultivation temperature. The expression levels of the chaperonins were examined by using specific antibodies at various cell growth temperatures in the logarithmic and stationary phases. At 60 degrees C, CpkA was highly expressed in both the logarithmic and stationary phases; however, CpkB was not expressed in either phase.

Expression profiles and physiological roles of two types of prefoldins from the hyperthermophilic archaeon Thermococcus kodakaraensis.

The hyperthermophilic archaeon Thermococcus kodakaraensis possesses four prefoldin genes encoding two alpha subunits (pfdA and pfdC) and two beta subunits (pfdB and pfdD) of prefoldins on the genome. pfdC and pfdD are unique genes whose orthologues are not found in Pyrococcus spp., whereas pfdA and pfdB are commonly found in both Thermococcus and Pyrococcus spp.

L-158,809 and (D-Ala(7))-angiotensin I/II (1-7) decrease PAI-1 release from human umbilical vein endothelial cells.

The endothelium is a major source of plasminogen activator inhibitor-1 (PAI-1), which plays a critical role in the regulation of fibrinolysis. There are many reports on the increase in the expression of PAI-1 by angiotensin II (Ang II). In the present study, we investigated the effects of angiotensin-related substances on the release of PAI-1 from human umbilical vein endothelial cells (HUVECs).