Publications by authors named "Masaya Shimokawatoko"
Article Synopsis
- Endocytosis-derived extracellular vesicles (EVs), which are tiny particles useful for disease prediction, face challenges in visualization due to their small size being below the optical diffraction limit.
- The study used a plasmonic chip to enhance the fluorescence of single EVs by capturing them and binding fluorescently labeled antibodies, allowing detection of even the smallest EVs as bright spots.
- Techniques involved included evaluating fluorescence intensity and distinguishing single EVs from larger aggregates, ultimately achieving the successful detection of single EVs with multiple targets at various wavelengths.
