Publications by authors named "Masatsugu Miyagawa"

Stent fracture is one of the complications of drug-eluting stent implantation. An 84-year-old man underwent coronary angiography for unstable angina. He had diffuse severe stenosis and calcified plaque in the left anterior descending artery and underwent percutaneous coronary intervention (PCI) in the left anterior descending artery for severe stenosis with chest pain.

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Background: Nonobstructive general angioscopy (NOGA) can identify vulnerable plaques in the aortic lumen that serve as potential risk factors for cardiovascular events such as embolism. However, the association between computed tomography (CT) images and vulnerable plaques detected on NOGA remains unknown.

Methods And Results: We investigated 101 patients (67±11 years; women, 13.

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Article Synopsis
  • * Researchers looked at 196 NSTE-ACS patients treated from March 2019 to October 2022 and divided them based on whether they had a CT scan and if it showed any perfusion defects.
  • * Findings indicated that patients with CT-detected perfusion defects had faster times from arrival to coronary angiography (CAG) and lower peak CK levels, suggesting that non-gated CT could aid in quicker diagnoses and treatments in NSTE-ACS cases. *
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Aims: Sodium-glucose co-transporter 2 (SGLT2) inhibitors have shown potential therapeutic benefits in heart failure (HF). However, data on their real-world usage and benefits in acute decompensated heart failure (ADHF) are limited.

Methods And Results: We conducted a post hoc analysis of real-world data from 1108 patients with ADHF admitted to Nihon University Itabashi Hospital (Tokyo, Japan) between 2018 and 2022.

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Atrial fibrillation (AF) is an independent risk factor for stroke and systemic embolism. Cardiogenic and aortogenic emboli are causes of stroke or systemic embolism. Non-obstructive general angioscopy (NOGA) can be used to diagnose aortic intimal findings, including thrombi and atherosclerotic plaques, but little is known about NOGA-derived aortic intimal findings in patients with AF.

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Article Synopsis
  • SGLT2 inhibitors like dapagliflozin may improve outcomes for patients with acute heart failure (AHF) when started early in treatment, but the optimal timing after hospital admission is unclear.
  • A study assessed 118 AHF patients, dividing them into early (E) and late (L) groups based on when they started dapagliflozin; results showed no major differences in heart failure severity between the groups.
  • Early initiation of dapagliflozin was linked to a significantly shorter hospital stay (16.5 days for E group vs. 22 days for L group), indicating it could be a crucial factor for reducing hospitalization time.
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Aims: Acute decompensated heart failure (ADHF) presents with pulmonary congestion, which is caused by an increased pulmonary arterial wedge pressure (PAWP). PAWP is strongly associated with prognosis, but its quantitative evaluation is often difficult. Our prior work demonstrated that a deep learning approach based on chest radiographs can calculate estimated PAWP (ePAWP) in patients with cardiovascular disease.

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Article Synopsis
  • The study examined how the angle of the left subclavian artery affects the duration of percutaneous coronary interventions (PCI) in patients with acute coronary syndrome (ACS).
  • Patients with a more tortuous artery (angles less than 70 degrees) were generally older, more likely to be female, and had higher rates of hypertension and artery calcification.
  • A significant negative correlation was found between the tortuosity of the artery and the time taken to complete the PCI, indicating that higher tortuosity leads to longer procedure times.
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There have been no reports on prognostic prediction and risk stratification based on stress phase bandwidth (SPBW), or a left ventricular (LV) mechanical dyssynchrony index, in patients with known or suspected stable coronary artery disease (CAD) at low or intermediate risk of major cardiac events (MCEs) using the J-ACCESS risk model. We retrospectively investigated 4,996 consecutive patients with known or suspected CAD who underwent rest Tl and stress Tc-tetrofosmin electrocardiogram (ECG)-gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) and followed up for 3 years to confirm their prognosis. MCE risk over 3 years was estimated using an equation based on that used in the J-ACCESS study.

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  • The study investigates the prognostic value of the MELD-XI scoring system in patients with acute decompensated heart failure (ADHF), focusing on changes in scores during hospitalization.
  • It categorized 536 patients based on their MELD-XI scores at admission and discharge into four groups: persistently normal, high-to-normal, normal-to-high, and persistently high, with the latter group facing the worst outcomes.
  • The results showed that patients with persistently high MELD-XI scores had a significantly higher rate of death or rehospitalization compared to the other groups, indicating the score's usefulness in predicting patient outcomes.
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There are no reports indicating a prognostic difference based on normalization of left ventricular (LV) mechanical dyssynchrony after revascularization in patients with coronary artery disease (CAD). We retrospectively investigated 596 patients who underwent rest Tl and stress Tc-tetrofosmin electrocardiogram-gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging. All patients had significant stenosis with ≥ 75% narrowing of the coronary arterial diameter detected by coronary angiography performed after confirmation of ≥ 5% ischemia by the SPECT.

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The role of the right to left ventricular (RV/LV) diameter ratio in predicating long-term outcomes in patients with pulmonary thromboembolisms (PTEs) treated with direct oral anticoagulants is unclear.We investigated the association between the RV/LV diameter ratio and clinical outcomes in PTE patients under rivaroxaban from the data of a multicenter, prospective, observational study (J'xactly Study) in Japanese patients with acute venous thromboembolisms (VTEs) including deep vein thromboses, PTEs, or both. Of a total of 1,039 patients with an acute VTE (from December 2016 to April 2018), 429 were diagnosed with PTEs, however, the population in this study consists of 216 patients in whom the RV/LV diameter ratio measured on the axial CT or transthoracic echocardiogram was available.

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Both cardiogenic shock (CS) and critical culprit lesion locations (CCLLs), defined as the left main trunk and proximal left anterior descending coronary artery, are associated with worse outcomes in ST-elevation myocardial infarctions (STEMIs). We aimed to examine how the combination of CS and/or CCLLs affected the prognosis in Japanese STEMI patients in the primary percutaneous coronary intervention era (PPCI-era). The subjects included 624 STEMI patients admitted to our hospital between January 2013 and April 2020.

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Article Synopsis
  • * It involved 771 patients admitted for acute HF, comparing those on public assistance with those having other forms of insurance, and found the former group had higher rates of certain health issues but received similar quality care during hospitalization.
  • * Despite comparable in-hospital outcomes, public assistance patients faced a significantly higher rate of cardiac events within one year post-discharge, indicating a need for enhanced follow-up care for these individuals.
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Objective This retrospective study was aimed at determining whether or not stress phase bandwidth (SPBW), a left ventricular (LV) mechanical dyssynchrony index, predicts major cardiac events (MCEs) and stratifies the risk of those in patients with coronary artery disease (CAD) who undergo revascularization. Methods Patients were followed up to confirm the prognosis for at least one year. The SPBW was calculated by a phase analysis using the Heart Risk View-F software program.

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Acute type B aortic dissection is sometimes complicated by acute respiratory failure requiring mechanical ventilation. Herein, we describe our experience in a rare acute type B aortic dissection-associated respiratory failure case culminating in acute respiratory distress syndrome. The patient was a 45-year-old man admitted with a complaint of sudden chest pain radiating to his back.

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Background And Aims: The optimal duration of dual antiplatelet therapy for acute myocardial infarction is controversial because the bleeding risk outweighs the thromboembolic risk. We hypothesized that an in-stent thrombus (IS-thrombus) detected by coronary angioscopy (CAS) after stent implantation would be associated with high bleeding risk.

Methods: This study included 208 patients who underwent CAS at 2 weeks after stent implantation for an acute myocardial infarction.

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