Publications by authors named "Masatsugu Kawahira"
Article Synopsis
- The study introduced a new method called tip detection (TD) combined with a special wire (CP12ST) to enhance the effectiveness of treating chronic total occlusion (CTO) in coronary procedures.
- Researchers compared the success rates and procedural times of the TD method with an existing technique (Stingray) using a different wire (CP20) in 54 total cases.
- The findings showed that the TD method led to a significantly higher success rate (100% vs 67%) and shorter procedural times (145 minutes vs 185 minutes), with few complications in both groups.
Article Synopsis
- Sleep apnea is common in patients undergoing catheter ablation for atrial fibrillation, and this study evaluates the effectiveness of watch-type peripheral arterial tonometry (WP) compared to polysomnography (PSG) in diagnosing sleep apnea severity.
- The study involved 464 patients and found that the apnea-hypopnea index (AHI) measured by WP was significantly lower than that measured by PSG, showing poor correlation overall.
- Only a small percentage of patients who needed CPAP treatment were identified by WP alone, highlighting the necessity of PSG for accurate diagnosis and treatment planning in sleep apnea for patients with atrial fibrillation.
Article Synopsis
- Researchers developed the GUIDE PLUS® 5Fr catheter and the GP-Lock method to enhance backup support during PCI (percutaneous coronary intervention) procedures.
- The GP-Lock method demonstrated the highest backup force of 293.7 gf compared to 270.4 gf for the KIWAMI-Lock method, and other conventional methods, highlighting its effectiveness.
- GP-Lock also reduced preparation time significantly (5 minutes) compared to KIWAMI-Lock (11 minutes), making it a more efficient option for complex PCI situations.
Objectives: The authors sought to elucidate the prognostic value of cardiac sympathetic nerve dysfunction as evaluated using iodine-123-labeled metaiodobenzylguanidine (I-MIBG) single-photon emission computed tomography (SPECT) imaging in patients with heart failure (HF) with preserved left ventricular ejection fraction (HFpEF).
Background: Cardiac sympathetic nerve dysfunction assessed by I-MIBG imaging is associated with poor outcomes in chronic HF patients with reduced left ventricular ejection fraction (HFrEF). However, no information is available on the prognostic vale of cardiac I-MIBG SPECT imaging in patients with HFpEF.
Background: Empagliflozin reduces the risk of hospitalization for heart failure in patients with type 2 diabetes and cardiovascular disease. We sought to elucidate the effect of empagliflozin as an add-on therapy on decongestion and renal function in patients with type 2 diabetes admitted for acute decompensated heart failure.
Methods: The study was terminated early due to COVID-19 pandemic.
Aims: Cardiohepatic interactions have been a focus of attention in heart failure (HF). The model for end-stage liver disease excluding international normalized ratio (MELD-XI) score has been shown to be useful for predicting poor outcomes in patients with acute decompensated HF (ADHF). Furthermore, the fibrosis-4 (FIB-4) index, a simple marker to assess liver fibrosis, predicts adverse prognoses in patients with HF as well.
View Article and Find Full Text PDFAims: Co-morbidities are associated with poor clinical outcomes in patients with chronic heart failure, while cardiac iodine-123 (I-123) metaiodobenzylguanidine (MIBG) imaging provides prognostic information in such patients. We sought to prospectively investigate the incremental prognostic value of cardiac MIBG imaging over the co-morbid burden, in patients admitted for acute decompensated heart failure (ADHF).
Methods And Results: In 433 consecutive ADHF patients with survival to discharge, we measured the co-morbidity using age-adjusted Charlson co-morbidity index (ACCI), commonly employed to evaluate a weighted and scored co-morbid condition, adding additional points for age.
Aims: Acute decompensated heart failure (ADHF) is generally treated by decongestion using diuretic therapy. However, the use of loop diuretics is associated with increased cardiac sympathetic nerve activity (CSNA). We aimed to evaluate the effect of adjunctive tolvaptan therapy on CSNA in ADHF patients with preserved left ventricular ejection fraction (LVEF).
View Article and Find Full Text PDFPrognostic significance of cardiac I-123-metaiodobenzylguanidine imaging in patients with reduced, mid-range, and preserved left ventricular ejection fraction admitted for acute decompensated heart failure: a prospective study in Osaka Prefectural Acute Heart Failure Registry (OPAR).
Eur Heart J Cardiovasc Imaging
January 2021
Aims: Cardiac 123I-metaiodobenzylguanidine (123I-MIBG) imaging provides prognostic information in patients with chronic heart failure (HF). However, there is little information available on the prognostic role of cardiac 123I-MIBG imaging in patients admitted for acute decompensated heart failure (ADHF), especially relating to reduced ejection fraction [HFrEF; left ventricular ejection fraction (LVEF) < 40%], mid-range ejection fraction (HFmrEF; 40% ≤ LVEF < 50%) and preserved ejection fraction (HFpEF; LVEF ≥ 50%).
Methods And Results: We studied 349 patients admitted for ADHF and discharged with survival.
Congestion is one of the main predictors of poor outcome in patients with heart failure (HF); thus, a simple tool to evaluate plasma volume (PV), which can be used for risk stratification of HF patients, is necessary. We sought to compare the prognostic values of commonly used formulas for the estimation of PV and relative PV status (PVS) in patients admitted with acute decompensated HF (ADHF). We analyzed 384 consecutive ADHF patients who survived to discharge.
View Article and Find Full Text PDFArticle Synopsis
- Nutritional status plays a critical role in the outcomes of patients with heart failure, and serum cholinesterase (CHE) is a key marker for assessing malnutrition and its impact on prognosis.
- This study aimed to investigate the significance of CHE levels in relation to other established nutritional indices (GNRI, CONUT, PNI) in patients experiencing acute decompensated heart failure (ADHF).
- Findings indicated that lower CHE concentrations were linked to higher rates of all-cause mortality, independent of other nutritional measures and patient demographics, highlighting the importance of CHE as a prognostic factor in this patient population.