Publications by authors named "Masatsugu Higuchi"
A 63-year-old woman had anti-Hu-associated paraneoplastic encephalomyelitis (anti-Hu syndrome) caused by esophageal small cell carcinoma (SCC). The patient developed bilateral limbic encephalitis, followed by myelitis, brain stem encephalitis, and autonomic failure. Extensive examination demonstrated SCC of the abdominal lymph nodes that was retrospectively diagnosed as metastasis of esophageal SCC on autopsy.
View Article and Find Full Text PDFArticle Synopsis
- The study measured levels of platelet-derived microparticles (PDMP) in patients with polymyositis and dermatomyositis (PM/DM) using an ELISA method to investigate platelet activation.
- Active PM/DM patients showed significantly higher PDMP levels compared to both treated patients and healthy controls, indicating a potential role of platelets in the disease's inflammatory process.
- A reduction in PDMP levels was observed after glucocorticoid treatment, and significant correlation with serum C-reactive protein levels suggests PDMP could serve as a useful marker for monitoring inflammation in PM/DM patients.
The intravenous immunoglobulin infusion therapy (IVIg) has recently acquired an important role in the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Some patients, however, require repetitive infusions to maintain the improvement. We planned a one-day therapy with 0.
View Article and Find Full Text PDF