Publications by authors named "Masatoshi Sekine"

Background: Cat cry syndrome is an autosomal disease accompanying abnormal deletion of chromosome 5 and occurs in only 1 of 50,000 neonates. Scoliosis has been reported as a skeletal complication in cat cry syndrome. The characteristics and causes of scoliosis in this rare syndrome are unknown.

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Synchronized firings in the networks of class 1 excitable neurons with excitatory and inhibitory connections are investigated, and their dependences on the forms of interactions are analyzed. As the forms of interactions, we treat the double exponential coupling and the interactions derived from it: pulse coupling, exponential coupling, and alpha coupling. It is found that the bifurcation structure of the networks depends mainly on the decay time of the synaptic interaction and the effect of the rise time is smaller than that of the decay time.

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The nonlinear prediction method based on the interspike interval (ISI) reconstruction is applied to the ISI sequence of noisy pulse trains and the detection of the deterministic structure is performed. It is found that this method cannot discriminate between the noisy periodic pulse train and the noisy chaotic one when noise-induced pulses exist. When the noise-induced pulses are eliminated by the grouping of ISI sequence with the genetic algorithm, the chaotic structure of the chaotic firings becomes clear, and the noisy chaotic pulse train could be discriminated from the periodic one.

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The globally connected active rotators with excitatory and inhibitory connections having different time constants under noise are analyzed using the nonlinear Fokker-Planck equation, and their oscillatory phenomena are investigated. Based on numerically calculated bifurcation diagrams, both periodic solutions and chaotic solutions are found. The periodic firings are classified based on the firing period, the coefficient of variation, and the correlation coefficient, and weakly synchronized periodic firings which are often observed in physiological experiments are found.

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Two cases of insufficiency fracture of the body of the calcaneus are presented to show its clinical presentation and diagnosis. It often is overlooked as a cause of pain in the ankle region. Both patients were elderly women with pain developing at the lateral aspect of the hindfoot in the absence of significant trauma.

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The globally connected active rotators with excitatory and inhibitory connections are analyzed using the nonlinear Fokker-Planck equation. The bifurcation diagram of the system is obtained numerically, and both periodic solutions and chaotic solutions are found. By observing the interspike interval, the coefficient of variance, and the correlation coefficient of the system, the relationship of our model to the biological data is discussed.

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Study Design: Peripheral sensory functions in patients with radiculopathy resulting from lumbar disc herniation and in control individuals were analyzed using current perception threshold testing.

Objective: To evaluate the severity of sensory disturbance quantitatively in patients with lumbar radiculopathy.

Summary Of Background Data: Subjective evaluation of the severity of sensory disturbance associated with spinal disorders using conventional methods often is difficult.

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