Publications by authors named "Masato Sakabe"
Article Synopsis
- Trichothecene biosynthesis starts with the transformation of farnesyl pyrophosphate into trichodiene, which is then oxygenated into isotrichotriol, followed by a non-enzymatic cyclization into isotrichodermol (ITDmol), a tricyclic precursor.* -
- Enzymes encoded by specific genes lead to several modifications of ITDmol, resulting in the formation of various toxic trichothecene metabolites; disruptions in these genes cause the accumulation of different tricyclic forms.* -
- The study found that the deletion of certain genes, particularly Tri3p, hampers the expected non-enzymatic transformations and leads to an accumulation of certain bicyclic
Invited for the cover of this issue are Masato Sakabe and Soichi Sato at Tokyo Metropolitan University. The image depicts the new hexacoordinated dicationic antimony species reported in this work. Read the full text of the article at 10.
View Article and Find Full Text PDFThe hexacoordinated antimony(V) dication [(ppy) Sb] ([1] ; ppy=2-(2-pyridyl)phenyl), stabilized by three intramolecular donor-acceptor interactions, has been isolated as its hexachloroantimonate salt [1][SbCl ] , prepared by the oxidative addition of chlorine to the neutral stibine [(ppy) Sb] (1), followed by the abstraction of chloride. Air-stable [1][SbCl ] exhibits remarkable thermal stability and the three ppy ligands on the antimony atom are shown to be magnetically inequivalent in the H and C NMR spectra. A hexacoordinated, meridional octahedral bonding geometry has been determined for [1][SbCl ] by X-ray crystallographic analysis.
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