Publications by authors named "Masashi Isetani"

Objectives: We evaluated the clinical outcomes of transumbilical single-incision laparoscopic appendectomy with extracorporeal hand-sewn stump closure in adults.

Methods: One-hundred-and-thirty-one consecutive adults with acute appendicitis were treated with the intention of performing transumbilical single-incision laparoscopic appendectomy with extracorporeal hand-sewn stump closure from July 2012 to December 2017. The procedure completion rate and outcomes were examined.

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  • A 67-year-old man with multiple liver metastases from metastatic colorectal cancer received TAS-102 combined with bevacizumab (Bmab) as a fifth-line chemotherapy treatment.* -
  • After 3 months on this regimen, imaging showed a 13% reduction in the size of the liver metastases.* -
  • The treatment was found to be safe and effective, with neutropenia being the most significant side effect, and the patient was able to continue for 6 months.*
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A case of colouterine fistula caused by colonic diverticulitis that was successfully treated laparoscopically is presented. A 74-year-old woman visited us with lower abdominal discomfort and vaginal excretion with minor fecal contamination. Mild tenderness was observed in her lower abdomen.

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  • * The authors present their experience with 6 cases of LLR involving major hepatic vein resection, detailing the types of surgeries performed, tumor sizes, operating times, blood loss, and hospital stays, all with no mortality and minimal complications.
  • * They propose a series of specific steps for conducting the procedure, leveraging the benefits of laparoscopy for better visibility and control during liver transection and vein division.
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Aim: To assess clinical outcomes of laparoscopic hepatectomy (LH) in patients with a history of upper abdominal surgery and repeat hepatectomy.

Methods: This study compared the perioperative courses of patients receiving LH at our institution that had or had not previously undergone upper abdominal surgery. Of the 80 patients who underwent LH, 22 had prior abdominal surgeries, including hepatectomy (n = 12), pancreatectomy (n = 3), cholecystectomy and common bile duct excision (n = 1), splenectomy (n = 1), total gastrectomy (n = 1), colectomy with the involvement of transverse colon (n = 3), and extended hysterectomy with extensive lymph-node dissection up to the upper abdomen (n = 1).

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  • - Hepatocellular carcinoma (HCC) is the leading primary liver cancer, often linked to chronic liver disease, making treatment complicated and reliant on various factors such as liver function and HCC stage.
  • - Liver resection (LR) is an effective treatment for HCC, with advances in imaging and surgical techniques improving 5-year survival rates to 38-61%, but it's only suitable for less than 30% of patients, and recurrence rates are high at around 80% within 5 years.
  • - Recent developments include enhanced preoperative planning with 3D imaging, the potential for laparoscopic surgery, and innovative therapies that could broaden the application of LR, alongside concepts like "bridging LR" and "sal
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  • Hepatocellular carcinoma (HCC) is the most common form of liver cancer, and its treatment is complicated by factors like the patient's liver condition, cancer stage, and overall health.
  • Liver resection (LR) is a highly effective treatment option, especially for early-stage HCC, with considerable survival rates improved by better liver function assessments and surgical techniques.
  • Liver transplantation (LT) is ideal for removing tumors and damaged liver tissue but is limited by graft availability and strict eligibility criteria, prompting interest in expanding donor options and exploring combined treatments with LR and LT.
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Pure laparoscopic hepatectomy is a less invasive procedure than conventional open hepatectomy for the resection of hepatic lesions. Increases in experiences with the technique, in combination with advances in technology, have promoted the popularity of pure laparoscopic hepatectomy. However, indications for usage and potential contraindications of the procedure remain unresolved.

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Aim: To study our novel caudal approach laparoscopic posterior-sectionectomy with parenchymal transection prior to mobilization under laparoscopy-specific view.

Methods: Points of the procedure are: (1) Patients are put in left lateral position and posterior sector is not mobilized; (2) Glissonian pedicle of the sector is encircled and clamped extra-hepatically and divided afterward during the transection; (3) Dissection of inferior vena cava (IVC) anterior wall behind the liver is started from caudal. Simultaneously, liver transection is performed to search right hepatic vein (RHV) from caudal; (4) Liver transection proceeds to the bifurcation of the vessels from caudal to cranial, exposing the surfaces of IVC and RHV.

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Solitary necrotic nodule of the liver is a rare benign lesion with a completely necrotic core and a hyalinized fibrotic capsule containing elastic fibers. The pathogenetic mechanism is still unclear. We here describe a case of SNN, whose central reticulin fibers within the nodule suggest the origin as hepatocellular carcinoma or other hepatocyte-origin tumors, treated with laparoscopic anatomical segmentectomy of the liver.

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