A synthetic tryptophan metabolite reduces hemorrhagic area and inflammation after pulmonary radiofrequency ablation in rabbit nonneoplastic lungs.

Purpose: The purpose of this study was to determine the effect of a synthetic tryptophan metabolite, tranilast [N-(3,4-dimethoxycinnamoyl)-anthranilic acid], on inflammatory and hemorrhagic areas after pulmonary radiofrequency ablation (RFA) in rabbits.

Materials And Methods: Percutaneous RFA using a 17-gauge LeVeen electrode was performed in normal rabbit lungs. The rabbits were divided into tranilast-treated (300 mg/kg/day, orally) and control groups (n = 24/group).

Loss of cellular viability in areas of ground-glass opacity on computed tomography images immediately after pulmonary radiofrequency ablation in rabbits.

Purpose: To determine cellular viability of lung parenchyma and neoplastic cells in areas of ground-glass opacity (GGO) on computed tomography (CT) images immediately after pulmonary radiofrequency ablation (RFA) in rabbits.

Materials And Methods: A LeVeen RFA electrode was placed percutaneously into rabbit lungs with or without metastatic VX2 tumors. Five minutes later, seven isolated lungs were imaged by use of a multi-detector row CT scanner, and the images were compared with histological features.

Comparison of diagnostic and prognostic capabilities of ¹⁸F-FDG-PET/CT, ¹³¹I-scintigraphy, and diffusion-weighted magnetic resonance imaging for postoperative thyroid cancer.

Purpose: The first aim of this study was to compare the detectability of metastasis of postoperative differentiated thyroid cancer (DTC) among (131)I whole body scintigraphy (IWBS), fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), and diffusion-weighted magnetic resonance imaging (DWI). The second aim was to clarify the association between the image pattern and prognosis.

Materials And Methods: We evaluated 70 postoperative DTC patients on both a patient basis and an organ basis (lymph nodes, lung, bone), and we analyzed the correlation between the image pattern and the prognosis.

Incidence of pulmonary embolism in younger versus older patients using CT.

Objective: The aim of this study is to compare the incidence of pulmonary embolism (PE) on computed tomography (CT) studies between younger and older patients to determine if there is an age-related bias for overutilization of CT pulmonary angiography (CTPA) in younger patients.

Material And Methods: Six hundred thirty-one consecutive CTPA cases for suspected acute PE between 11/10/2003 and 3/19/2004 were retrospectively studied. Of these 631 cases, 59 patients were found to have clots in the pulmonary arteries (ranging from central to subsegmental PA).

High-resolution computed tomography findings of P. westermani.

Paragonimiasis westermani, or Oriental lung fluke, is a common parasitic zoonosis, which is acquired from eating the flesh of wild boar or freshwater crabs. After being ingested by humans, the larvae of P. westermani migrate across small intestinal mucosa into the intra-abdominal space, and then finally into to the pleural space and lung parenchyma.

Bronchomalacia in sarcoidosis: evaluation on volumetric expiratory high-resolution CT of the lung.

Rationale And Objectives: The aim of this study is to investigate the frequency of bronchomalacia associated with sarcoidosis and compare the extent of air trapping in patients with sarcoidosis with and without bronchomalacia.

Materials And Methods: Eighteen consecutive patients (6 men, 12 women; age, 29-64 years; mean age, 47 years) with pathologically proven sarcoidosis who underwent clinical volumetric expiratory high-resolution computed tomography were studied. On contiguous end-expiratory images, the presence and severity of bronchomalacia and extent of air trapping were evaluated.

Sagittal reformations of volumetric inspiratory and expiratory high-resolution CT of the lung.

Rationale And Objectives: The purpose of this study is to determine whether sagittal reformations of volumetric high-resolution computed tomography (CT) provide additional information in evaluating lung abnormalities compared to axial high-resolution CT images.

Materials And Methods: Twenty-two consecutive patients who underwent combined inspiratory and expiratory volumetric high-resolution CT from May to July 2003 were studied. Using end-inspiratory and end-expiratory sagittal reformatted images, respiratory motion artifacts were evaluated at upper, middle, and lower lung areas bilaterally.

[Usefulness of 201Tl SPECT in the predication of mediastinal lymph nodes metastasis in patients with non small cell lung carcinoma (NSCLC)].

Predictivity of mediastinal lymph nodes metastasis of 201Tl SPECT were examined before operation in 113 patients with non-small cell lung cancer (69 adenocarcinoma, 31 squamous cell carcinoma, 10 large cell carcinoma, 2 bronchiolo-alveolar carcinoma, 1 neuroendocrine cell carcinoma). Patients were classified into two groups, with or without lymph nodes metastasis according to the pathological diagnosis. We calculated parameters of 201Tl SPECT early ratio, delayed ratio, retention index (RI) and maximal diameters.

Coronal reformations of volumetric expiratory high-resolution CT of the lung.

Objective: The purposes of this study were to evaluate the quality of coronal reformatted images obtained from volumetric expiratory high-resolution CT imaging and to compare coronal and axial images with regard to their usefulness in detecting and characterizing air trapping. SUBJECTS AND METHODS. We studied 40 consecutive patients with known or suspected diffuse lung diseases with airway abnormalities who underwent volumetric expiratory high-resolution CT between May and July 2003.

Minute pulmonary meningothelial-like nodules: high-resolution computed tomography and pathologic correlations.

Minute pulmonary meningothelial-like nodules (MPMNs), previously known as minute pulmonary chemodectomas, are relatively rare lesions. They are small (1-3 mm) and often multiple. Pathologically, they represent an interstitial nodular proliferation of small oval or spindle-shape cells arranged in a "zellenballen" nesting pattern.