Publications by authors named "Masanori Beppu"

Article Synopsis
  • - This study aimed to assess the effectiveness of a formulated food containing Peucedanum japonicum extract and saw palmetto extract in improving urination issues in men with lower urinary tract symptoms (LUTS) over a 4-week period.
  • - Patients showed significant improvement in subjective symptom scores, especially in quality of life related to urination, nocturia frequency, and overall satisfaction; objective measures like residual urine volume also decreased significantly.
  • - The treatment was well-received, with no adverse effects reported, and 75% of participants rated their experience positively, with many wanting to continue the treatment afterward.
View Article and Find Full Text PDF

Purpose: Prostaglandins have been implicated as endogenous modulators of bladder function under physiological and pathological conditions. We examined how the expression of each EP receptor subtype changed in association with bladder outlet obstruction and focused on the functional role of EP4 receptor subtype in the bladder with outlet obstruction.

Materials And Methods: We assessed the gene expression of EP receptor subtypes by reverse transcriptase-polymerase chain reaction.

View Article and Find Full Text PDF

Objectives: To examine the possibility that mechanosensitive ion channels, including epithelial Na+ channels (ENaC), are implicated in mechanosensory transduction of the rat urinary bladder.

Methods: Cystometry with continuous infusion was performed to investigate the effect of intravesically perfused amiloride (a blocker of ENaC) on micturition reflex in urethane-anesthetized female rats. Bladder strips with or without epithelium suspended in organ bath were subjected to varying degrees of mechanical stretch (up to 50%).

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on the prevalence of urinary incontinence (UI) among working women in Japan, finding that 16.7% of the surveyed nurses reported experiencing UI, primarily stress UI.
  • Results indicated that UI negatively affected quality of life (QOL), particularly in areas like physical and mental health, with younger women facing more significant physical health impacts, while older women reported greater effects on mental health.
  • The findings highlight an age-related increase in the prevalence of UI, peaking at ages 45 to 49, suggesting a need for more awareness and support for affected women at different life stages.
View Article and Find Full Text PDF