Publications by authors named "Masamichi Tomonaga"

Background: Immunotherapy is useful for the prevention of the post-operative recurrence of some types of cancer and, in combination with certain anticancer drugs, is expected to prolong survival time. However, the clinical efficacy of immunotherapy alone against advanced cancer has not yet been demonstrated.

Case Report: A 67-year-old woman with ovarian cancer who had undergone post-operative adjuvant chemotherapy suffered from recurrent cancer in the lymph nodes.

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Background: The beneficial effects of immunocell therapy, using either activated lymphocytes (ALs) or dendritic cells (DCs), in the treatment of melanoma has been demonstrated. DCs are professional antigen-presenting cells that induce cytotoxic T lymphocytes against tumor cells. DC therapy may be promising when combined with ALs.

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Background: Patients with advanced pancreatic carcinoma have a risk of relapse after primary therapy, and the prognosis for these patients remains bleak. The effect of immuno-cell therapy in advanced pancreatic carcinoma, with or without other standard therapies, was examined.

Patients And Methods: Forty-six patients with advanced pancreatic carcinoma, undergoing immuno-cell treatment, were evaluated.

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The purpose of the study is to elucidate the effects of a craniotomy on patients regarding the cytokines and immunological function. TNF-alpha, IL-6, the CD4/8 ratio, cortisol, and WBC were all measured perioperatively in 29 patients. No serum TNF-alpha was detectable in any patients.

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Objective: To clarify the efficacy of chemotherapy after radiation therapy in immunocompetent patients with primary central nervous system lymphoma (PCNSL).

Patients And Methods: A retrospective analysis of 22 PCNSL patients was performed. Twenty-two patients were divided into a combined treatment (chemotherapy after radiation) group and a radiation group.

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