A 64-year-old man with no previous medical history underwent catheter ablation (CA) by right pulmonary vein isolation and creation of an anteroseptal mitral isthmus (MI) line for peri-mitral atrial flutter. Since atrial tachycardia (AT) recurred with palpitation 4 months later, a second CA session was performed. Although the differential pacing method appeared to confirm the conduction block across the MI line previously created, single-loop bi-atrial AT (Bi-AT) involving both atria through the septum was induced.
View Article and Find Full Text PDFDirect-current (DC) cardioversion is effective at terminating arrhythmias in an emergency. During treatment, energy delivery synchronizing with the QRS complex is essential to avoid ventricular fibrillation (VF) caused by a shock on the T wave, which is the vulnerable period of ventricular repolarization. However, distinguishing the QRS from the T wave is difficult in some patients with abnormal, irregular, and varying QRS complexes.
View Article and Find Full Text PDFBackground: In 2013, the Centers for Disease Control and Prevention (CDC) issued the concept of the ventilator-associated events (VAEs) as a quality indicator (QI) in the intensive care unit (ICU). A number of studies have been conducted in the United States and other Western countries to evaluate its practicality. However, information on VAEs in non-Western countries is scarce.
View Article and Find Full Text PDFAim: This study sought to determine the human papillomavirus (HPV)-16 E7 epitopes that would be presented by HLA-DR molecules to CD4-positive T cells in patients with cervical carcinoma.
Methods: HLA-DR binding assays were performed using HPV-16 E7-derived synthetic peptides and, after incubation with these DR-binding peptides, helper T cell frequencies were analyzed in patients whose HLA and HPV genotypes were confirmed.
Results: We determined that the E7d peptide, 61CDSTLRLCVQSTHVDIRTL80E, was bound by HLA-DRB1*0901.