Publications by authors named "Masakuni Tokuda"
The prevalence of metabolic syndrome is increasing in children and adolescents. Although some diagnostic criteria for metabolic syndrome exist, further research is needed to determine appropriate age-, sex-, and race-specific cutoffs for each component. Health examinations were conducted in 1,679 children aged 6-15 years in 9 regions of Japan.
View Article and Find Full Text PDFBackground: The associations between developmental patterns (trajectories) in children and maternal factors have been widely investigated, but paternal effects on these trajectories are unclear. This study aimed to determine child and parental factors involved in developmental trajectories at high risk for causing adverse cardiovascular (CV) profiles in children.
Methods: We analyzed longitudinal anthropometric data from birth to the present and CV profiles of 1,832 healthy volunteers (51% girls) aged 3-15 years who participated in a nationwide study between July 2012 and January 2014.
Article Synopsis
- About twice as many boys as girls receive growth hormone therapy for growth hormone deficiency (GHD), but this may be due to a selection bias rather than actual prevalence.
- A study involving 3,902 children at 17 short stature clinics found no significant difference in the percentage of boys (45.7%) and girls (49.8%) undergoing GH stimulation tests, nor in the diagnosis rates of GHD (22.0% for boys vs. 20.1% for girls).
- The observed boy-to-girl ratio in both short stature and GHD diagnoses was similar (1.58:1 and 1.59:1 respectively), suggesting that more boys seek treatment due to parental concerns about boys' height
Article Synopsis
- A randomized controlled trial in Japan aimed to assess the impact of walking on childhood obesity among elementary school children with a high percentage overweight (≥20%).
- Participants were divided into three groups: one encouraged to walk at least 10,000 steps on school holidays, another to limit screen time, and a control group with no intervention, with a primary outcome of %OW reduction after three months.
- Results showed that the walking group experienced a significant decrease in %OW (mean reduction of -4.06%) compared to the control group, suggesting that promoting walking can be an effective strategy for addressing obesity in children.
Investigation on hyperuricemia in children with obesity or various pediatric disorders.
Nucleosides Nucleotides Nucleic Acids
December 2011
The present study aims at investigating the frequency and characteristics of hyperuricemia in both obese and sick children. First, we established our own reference values for serum uric acid (UA), since UA values are highly dependent upon age. In the analysis of 328 samples consisting of six different age groups: <1, 1-3, 4-6, 7-9, 10-12, and 13-15 years, the mean values for UA were found to increase significantly with an increase of age.
View Article and Find Full Text PDFThe prevalence of hyperuricemia in obese children and adolescents and its association with metabolic syndrome are largely unknown. The objective of our study was to characterize hyperuricemia in relation to metabolic syndrome in Japanese children and adolescents with obesity. Between 2005 and 2008, we performed a cross-sectional study of 1,027 obese children and adolescents aged 6-14 years.
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