Publications by authors named "Masako Funaki"
Article Synopsis
- Familial adenomatous polyposis (FAP) is an inherited disorder caused by mutations in the APC gene, leading to colorectal polyps and other health issues.
- This condition can also cause extracolonic manifestations like desmoid tumors and various mental disorders in affected families.
- A case study highlights the importance of mental health care in genetic counseling, as a family with FAP showed connections between the disorder and mental health issues, including autism spectrum disorder and intellectual disabilities.
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) featuring numerous neuropathologies, including optic neuritis (ON) in some patients. However, the molecular mechanisms of ON remain unknown. Galectins, β-galactoside-binding lectins, are involved in various pathophysiological processes.
View Article and Find Full Text PDFExpression and regulation of adrenomedullin in renal glomerular podocytes.
Biochem Biophys Res Commun
April 2005
Adrenomedullin (AM) is postulated to exert organ-protective effects. It is expressed in the renal glomeruli, but its roles in the glomerular podocytes have been poorly elucidated. In the present study, we investigated the expression and regulation of AM in recently established conditionally immortalized mouse podocyte cell line in vitro and podocyte injury model in vivo.
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