O2 saturation in the intercostal space during moderate and heavy constant-load exercise.

To examine the hypothesis that the relationship between minute ventilation (VE) and deoxygenation from the intercostal space (IC) would be steady regardless of exercise protocols, if an increase in O2 consumption of the accessory respiratory muscles with an increase of VE brings about deoxygenation in IC, we measured the relationship between VE and O2 saturation in IC (SO2IC) during a constant-load exercise test (CET), and the relationship was compared with that during a ramp incremental exercise test (RIET). Six male subjects performed RIET. On a different day, the subjects performed a moderate and heavy CET (CET_MOD and CET_HVY, respectively).

Transoral open reduction with rigid internal fixation for subcondylar fractures of the mandible using a small angulated screwdriver system: is endoscopic assistance necessary?

Purpose: Although endoscopically assisted transoral open reduction and internal fixation of condylar mandible fractures is currently a popular technique, the need for it and its benefits remains unclear. This prospective study evaluated the efficacy and safety of open reduction and rigid internal fixation of subcondylar fractures of the mandible using a new small angulated screwdriver system without endoscopic assistance.

Patients And Methods: Fifteen patients with 15 linear subcondylar fractures were treated using this intraoral approach from June 2007 through March 2010 at the Division of Oral and Maxillofacial Surgery, Kagawa Prefectural Central Hospital, Kagawa, Japan.

Oral rehabilitation of a maxillectomy defect using bone transport distraction and dental implants.

Bone transport distraction is a reliable procedure in various maxillofacial bony defect reconstruction techniques. It is minimally invasive and it eliminates donor site morbidity. We introduce a new surgical technique for maxillary backward bone transport distraction reconstruction performed in a 77-year-old woman with a posterior partial maxillary defect.

Comparison of muscle O(2) dynamics at different sites of the forearm flexor muscles during incremental handgrip exercise.

This study investigated heterogeneity of muscle O(2) consumption (diffusive m-VO(2)) and muscle oxygenation difference (m-O(2) difference) within the forearm flexor muscles using multi-optical fibers near-infrared continuous wave spectroscopy (NIRcws) during incremental exercise. Nine healthy male subjects performed incremental dynamic handgrip exercise until exhaustion. The workload was increased by 5% maximal voluntary contraction (MVC) every 1 min, starting at 10% MVC.

Unchanged muscle deoxygenation heterogeneity during bicycle exercise after 6 weeks of endurance training.

The purpose of this study was to examine the changes in muscle oxygen saturation (SmO(2)) level and its heterogeneity after 6 weeks of endurance training using multi-channel near infrared spatially resolved spectroscopy (NIR(SRS)). Nine healthy subjects participated in this study (Male = 6, Female = 3, age: 27 +/- 5 years, height: 168.7 +/- 7.

Clinicopathological analysis of colorectal cancers in the elderly.

The average life expectancy of Japanese is 78 years for males and 85 years for females, being the longest in the world. In this study, elderly patients with colorectal cancer who underwent surgery and their non-elderly counterparts were compared to characterize the elderly patients. Of 387 colorectal cancer patients, 98 were over 75 years old, and 106 were between 45 and 60 years of age.

Cloning of a novel splicing variant of RIN1 and its expression in gastric and colon cancer.

The regular RIN1 gene is a molecule located on chromosome 1lq13.2, and contains a coding region of 2352 bp with a 3' domain that binds to H-Ras protein, suggesting that it is an important molecule in the intracellular signaling pathway. In this study, we confirmed the existence of a novel form of the RIN1 gene with a different splicing pattern, successfully cloned it, and examined its expression in gastric and colon cancer cell lines.

Submandibular approach through the submandibular gland fascia for treating mandibular fractures without identifying the facial nerve.

Background: : The submandibular, or Risdon, approach is the classic, reliable extraoral approach for treating mandibular fractures. Although the intraoral approach has been used recently for open reduction and internal fixation, in some cases, such as comminuted fractures or fractures in an atrophic mandible, the submandibular approach is still prerequisite. Damage to the marginal mandibular branch of the facial nerve is the only concern other than skin scarring.

Clinicopathological study of the colorectal mucinous carcinomas.

Histopathologically, the incidence of mucinous carcinomas in Europe and the United States is approximately 10% and that in Japan is low, at 2.9% to 7.4%.

Angiogenesis and tumor proliferation/metastasis of human colorectal cancer cell line SW620 transfected with endocrine glands-derived-vascular endothelial growth factor, as a new angiogenic factor.

Endocrine glands-derived-vascular endothelial growth factor (EG-VEGF) was recently cloned as a new angiogenic factor that selectively acts on the endothelium of endocrine gland cells. We evaluated the involvement of EG-VEGF in colorectal cancer. The expression of EG-VEGF was confirmed in all of the colorectal cancer cell lines.

[Significance of peritonectomy for peritonitis carcinomatosis].

We analyzed patients who underwent multimodal treatment with peritonectomy as an aggressive treatment for peritonitis carcinomatosis. Peritonectomy was treated in eighteen cases (eleven gastric cancer, seven colon cancer). Out of these eighteen cases, nine were initial operation, six were recurrence after first operation and three were for relief after palliative operation for peritoneal dissemination.