Publications by authors named "Masaki Katsurahara"

A 68-year-old female patient was referred to our hospital with a 30-mm polyp in the second portion of the duodenum found via esophagogastroduodenoscopy. The polyp had an irregular, lobular surface and a thick stalk. In addition, white dots were detected on the surface.

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Background: Endoscopic submucosal dissection (ESD) for superficial esophageal cancer is technically challenging, and research on predictive factors related to the difficulty in the procedure is limited. This study aimed to investigate the factors predicting the difficulty in esophageal ESD.

Methods: This retrospective study analyzed 303 lesions treated at our institution between April 2005 and June 2021.

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Superficial epithelial gastric neoplasms can be divided into adenomas and early carcinomas. Histological diagnosis by endoscopic forceps biopsy is crucial for the diagnosis and management of gastric neoplasms. It is difficult to distinguish features of gastric neoplasms in small biopsy specimens; hence, gastric carcinomas can be underdiagnosed as adenomas.

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Magnifying endoscopy with narrow band imaging (M-NBI) was developed to diagnose Barrett's esophageal adenocarcinoma (BEA); however, this method remains challenging for inexperienced endoscopists. We aimed to evaluate a modified M-NBI technique that included spraying acetic acid (M-AANBI). Eight endoscopists retrospectively examined 456 endoscopic images obtained from 28 patients with 29 endoscopically resected BEA lesions using three validation schemes: Validation 1 (260 images), wherein the diagnostic performances of M-NBI and M-AANBI were compared - the dataset included 65 images each of BEA and non-neoplastic Barrett's esophagus (NNBE) obtained using each modality; validation 2 (112 images), wherein 56 pairs of M-NBI and M-AANBI images were prepared from the same BEA and NNBE lesions, and diagnoses derived using M-NBI alone were compared to those obtained using both M-NBI and M-AANBI; and validation 3 (84 images), wherein the ease of identifying the BEA demarcation line (DL) was scored via a visual analog scale in 28 patients using magnifying endoscopy with white-light imaging (M-WLI), M-NBI, and M-AANBI.

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Background: Helicobacter pylori infection is a well-recognized cause of gastric diseases, including chronic gastritis, peptic ulcer, and gastric cancer. Vacuolating cytotoxin-A (VacA) and cytotoxin-associated gene A protein (CagA) play a role in the pathogenesis of H. pylori-related gastric diseases.

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Article Synopsis
  • - Liposarcoma attached to the mesentery is very rare and often hard to properly diagnose, as seen in a 70-year-old woman who had a mass in her right lower abdomen.
  • - After surgery to remove the mass, she was found to have dedifferentiated liposarcoma originating from the transverse colon and began chemotherapy.
  • - Diagnosing this type of cancer based solely on imaging is difficult, so surgery can help; additionally, genetic testing was done since new treatments for dedifferentiated liposarcoma are being researched.
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  • A 64-year-old man with diabetes and gallstones was suspected of having pancreatic cancer after imaging showed cysts and fluid accumulation around the abdomen.
  • Further evaluation through endoscopic ultrasonography identified a mass in the pancreas, but biopsy results did not show cancer, leading to a suspicion of type 1 autoimmune pancreatitis.
  • The patient was treated with prednisolone, and follow-up CT scans after 11 days showed a reduction in the size of the cysts and ascites.
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  • Endoscopic submucosal dissection (ESD) is an effective, minimally invasive treatment for superficial esophageal cancer (SEC) that often results in complete tumor removal.
  • This study analyzed the outcomes of ESD in 318 SEC patients, comparing those who had undergone gastrectomy to those who hadn't, using propensity-score matching to reduce bias.
  • Results showed no significant differences in key outcomes such as resection rates, procedure duration, hospitalization time, or recurrence between gastrectomized and non-gastrectomized patients, suggesting gastrectomy history does not adversely affect ESD effectiveness.
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A 44-year-old woman presented with severe anemia. We strongly suspected gastrointestinal bleeding; however, esophagogastroduodenoscopy, colonoscopy, and computed tomography showed no bleeding sources. Video capsule endoscopy revealed an actively bleeding submucosal lesion within the jejunum.

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Background: This study aimed to clarify the features of superficial non-ampullary duodenal epithelial tumors (SNADETs) on magnifying endoscopy with narrow-band imaging (M-NBI) and magnifying endoscopy with acetic acid and narrow-band imaging (M-AANBI), and evaluate the efficacy of M-NBI/M-AANBI to distinguish high-grade adenomas or adenocarcinomas (HGA/AC) from low-grade adenomas (LGA).

Methods: Clinicopathological data on 62 SNADETs in 58 patients who underwent preoperative M-NBI/M-AANBI and endoscopic resection were retrospectively reviewed. The pathological results were classified into two categories, LGA and HGA/AC.

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Background: Narrow-band imaging (NBI) highlights the surface structures and vessels of colorectal polyps and is useful for determining the polyp histology. The narrow-band imaging international colorectal endoscopic (NICE) classification is a diagnostic tool for determining colorectal polyp histology based on NBI without optical magnification. In this study, we aimed to investigate the value of each type of the NICE classification for determining colorectal polyp histology using endoscopy data accumulated in a clinical setting.

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  • Female patients often experience increased pain during unsedated colonoscopy, prompting this study to test a small-caliber colonoscope, PCF-PQ260 L, for pain reduction.
  • The study involved 220 women, split between the small-caliber and standard colonoscopy groups, with results showing that those using the small-caliber scope reported significantly lower overall and maximum pain scores.
  • Additionally, the small-caliber colonoscope not only improved the success rate of the procedure but also increased the likelihood of women opting for unsedated colonoscopies in the future.
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Background: The role of in the pathogenesis of reflux esophagitis is controversial. This study investigated the frequency of reflux esophagitis before and after eradication in patients having endoscopic submucosal dissection for early gastric cancer.

Methods: This study included 160 patients that fulfilled the study's criteria.

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  • This study assessed the effectiveness of endoscopic submucosal dissection using the pocket-creation method (ESD-PCM) with a HookKnife for treating small rectal neuroendocrine tumors (NETs).
  • It reviewed data from 12 patients who underwent this procedure, finding a high success rate (R0 resection) and no adverse events.
  • The results indicated that ESD-PCM is a promising technique for removing rectal NETs, supported by accurate preoperative evaluation through endoscopic ultrasonography (EUS).
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  • A 22-year-old man with upper abdominal pain had imaging tests showing a complex mass in the liver region.
  • Imaging suggested the mass could be a hematoma or a neoplastic disease, leading to surgical resection.
  • The final diagnosis was abdominal lymphangioma, a rare and benign tumor, highlighting the need to include it in differential diagnoses for similar abdominal masses.
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Colorectal involvement is very rare in cases of follicular lymphoma. Colonoscopy of a 69-year-old man revealed an aggregation of multiple whitish nodules in the sigmoid colon. Magnifying endoscopy with narrow-band imaging demonstrated a coiled and elongated microvascular pattern on the surface and crystal violet staining showed a type I pit pattern.

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