Publications by authors named "Masahito Kokubu"
A 70-year-old woman presented with stage III pancreatic head cancer. After endoscopic sphincterotomy, a fully covered self-expandable metallic stent (FCSEMS) was placed in the common bile duct to manage jaundice. The patient developed a fever and abdominal pain 40 days after stent placement, with a suspected diagnosis of infected pancreatic pseudocyst.
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- - The study examined the effectiveness of S-1 and modified FOLFIRINOX (mFFX) as second-line treatments for unresectable pancreatic cancer (UPC) after patients failed gemcitabine plus nab-paclitaxel (GnP) therapy, noting that results for these options have limited documentation.
- - Out of 86 UPC patients, 41 received S-1 and 21 received mFFX, with mFFX generally prescribed to younger patients in better health; both treatments showed similar average progression-free and overall survival durations.
- - While S-1 had a lower rate of severe side effects (20%) compared to mFFX (57%), the latter led to a higher response rate