Post Stroke Mirror Movements Preventing Performance of Bilateral Movements and Activities of Daily Living.

Mirror movements (MMs) are involuntary synchronous movements of one limb during voluntary movements of the contralateral limb. Generally, MMs after stroke are observed in the unaffected hand during voluntary movements of the affected hand; MMs in the affected hand are comparatively rare. In previous studies, evaluation of MMs in the affected hand was performed using simple unilateral movement tasks, such as tapping or forceful repeated hand closure.

Asymmetry of Interhemispheric Connectivity during Rapid Movements of Right and Left Hands: A TMS-EEG Study.

The interhemispheric signal propagation (ISP) obtained by electroencephalography during transcranial magnetic stimulation (TMS) allows for the assessment of the interhemispheric connectivity involved in inhibitory processes. To investigate the functional asymmetry of hemispheres during rapid movement, we compared ISP in the left and right hemispheres during rapid hand movements. In 11 healthy right-handed adults, we delivered TMS to the M1 and recorded ISP from the M1 to the contralateral hemisphere.

Relationship Between Motor Function, DTI, and Neurophysiological Parameters in Patients with Stroke in the Recovery Rehabilitation unit.

Objectives: We investigated the relationship between pyramidal tract evaluation indexes (i.e., diffusion tensor imaging, transcranial magnetic stimulation (TMS)-induced motor-evoked potential (MEP), and central motor conduction time (CMCT) on admission to the recovery rehabilitation unit) and motor functions at discharge in patients with ischemic or hemorrhagic stroke.

Modulation of redox potential and alteration in reactivity via the peroxide shunt pathway by mutation of cytochrome P450 around the proximal heme ligand.

In the thermophilic cytochrome P450 from the thermoacidophilic crenarchaeon Sulfolobus tokodaii strain 7 (P450st), a phenylalanine residue at position 310 and an alanine residue at position 320 are located close to the heme thiolate ligand, Cys317. Single site-directed mutants F310A and A320Q and double mutant F310A/A320Q have been constructed. All mutant enzymes as well as wild-type (WT) P450st were expressed at high levels.