Publications by authors named "Masahiro Takami"
Background: Metastasis occurs as a late event in the natural history of hepatocellular carcinoma (HCC), and most patients die of liver failure attributed to the tumor supplanting the liver. Conversely, the brain is a less common metastatic site.
Case Summary: We describe a rare case of hepatitis C virus-related multiple HCC metastasizing to the cavernous sinus, Meckel's cave, and the petrous bone involving multiple cranial nerves in an 82-year-old woman.
Article Synopsis
- The study investigated how oxidative stress and thromboxane A (TXA) contribute to kidney damage in hypertension using a specific rat model (SHRSP).
- It was found that SHRSP exhibited significantly higher levels of thromboxane synthase (TXAS) mRNA in their kidneys compared to normal rats, alongside increased heme oxygenase-1 mRNA.
- Surprisingly, treating SHRSP with tempol (an antioxidant) worsened kidney damage, while using ozagrel (a TXAS inhibitor) improved it, suggesting that targeting TXA may be more effective than focusing on oxidative stress for treating kidney injuries in hypertension.
Cryoglobulinemia can induce systemic vasculitis affecting various organs such as skin, peripheral nerves, and kidney. The disease can induce chronic organ failure and even be life-threatening. Cryofiltration has been applied for the treatment of cryoglobulinemic vasculitis.
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