Efficacy of the continuous use of a lotion with carbon dioxide on male subjects with mild acne.

Objective: Acne vulgaris is caused by dyslipidemia, dyskeratosis and/or abnormal bacterial growth. The obstruction of skin pores due to hyperkeratosis of the infundibulum contributes to the formation of comedones. Thus, normalizing keratinization of epidermal cells in skin pores might be useful to improve acne.

Evaluation of subclinical chronic sun damage in the skin via the detection of long-lasting ultraweak photon emission.

Background: It is well known that solar radiation accelerates skin photoaging. To evaluate subclinical photodamage in the skin especially from the early phase of ultraviolet (UV)-induced damage, we have focused on ultraweak photon emission (UPE), also called biophotons. Our previous study reported that the amount of long-lasting UPE induced by UV, predominantly from lipid peroxidation, is a valuable indicator to assess cutaneous photodamage even at a suberythemal dose, although it was only applied to evaluate acute UV damage.

Efficacy of a moisturizer containing a pseudo-ceramide and a eucalyptus extract for Japanese patients with mild atopic dermatitis in the summer.

Background: Skin moisturizing is advocated to take care of the skin of patients with atopic dermatitis (AD). However, many patients stop using moisturizers in the summer because of excessive sweating and high humidity.

Objectives: To examine the efficacy of a moisturizing gel containing a pseudo-ceramide and a eucalyptus extract, which enhances epidermal ceramide synthesis of patients with mild AD in the summer.

The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin.

Objective: Dry and scaly conditions on the scalp are often observed in patients with atopic dermatitis, seborrheic dermatitis and/or pityriasis capitis. Those scalp lesions often exhibit low barrier function and reduced ceramide levels. Therefore, a clinical study was conducted to evaluate the efficacy of topical application of a pseudo-ceramide and eucalyptus extract-containing lotion on the scalps of patients with skin diseases.

A cleanser based on sodium laureth carboxylate and alkyl carboxylates washes facial sebum well but does not induce dry skin.

Background: Because excess sebum and/or metabolites of sebum induce skin problems, cleansers that can remove those kinds of sebum are sought after. However, many people, especially who have little facial sebum, are afraid to wash off sebum well because that may induce dry skin. This concern may be caused by the result that cleansers with a high cleansing ability tend to decrease not only facial sebum but also natural moisturizing factors and intercellular lipids that are essential for cutaneous function.

Precipitate deposition around CMC and vesicle-to-micelle transition of monopotassium monododecyl phosphate in water.

Monoalkyl phosphate (MAP) salts are a kind of bivalent anionic surfactants. The difference of properties between half-neutralized monosalt and completely neutralized disalt is very interesting. In this study, the aggregation behavior of monopotassium monododecyl phosphate (MAP-12K) in aqueous solution with an increase in concentration was investigated by surface tension (γ), elemental analysis, gas chromatography, differential scanning calorimetry, steady-state fluorescence, and negative strained transmission electron microscopy techniques.

Relationship between microstructure of the skin surface and surface reflection based on geometric optics.

Background: The behavior of reflected light in skin affects skin appearance and provides clues as to the internal condition of the skin. Surface topography is one of the central physical factors contributing to surface reflection.

Objective: We tried to clarify the relationship between microstructure of the skin surface and surface reflection based on geometric optics.