Ischemia/reperfusion in rat heart induces leptin and leptin receptor gene expression.

Concentrations of leptin, an adipocyte-derived hormone, are elevated in obesity. Recently, leptin has been shown to participate in multiple biological actions including inflammation, reproduction, and angiogenesis. Leptin has also been documented as a critical component in the process of wound healing; however, leptin involvement in cardiovascular disease is poorly understood.

Effect of dog-walking on autonomic nervous activity in senior citizens.

Objective: To compare changes in autonomic nervous activity in healthy senior individuals while walking with and without a dog, and during routine activities at home and periods of interacting with the dog at home.

Design: Controlled crossover study.

Participants And Setting: 13 healthy volunteers (3 men, 10 women; mean age, 67.