Evaluation of dye decolorization using anaerobic granular sludge from an expanded granular sludge bed based on spectrometric and microbiome analyses.

The decolorization of 11 dyes by granular sludge from an anaerobic expanded granular sludge bed (EGSB) reactor was evaluated. Biological decolorization of Reactive Red 21, 23, and 180, and Reactive Yellow 15, 17, and 23 in model textile wastewater was observed for the first time after a 7-day incubation (over 94% decolorization). According to the sequencing analysis of 16S rRNA gene amplicons from EGSB granular sludge, the operational taxonomic unit related to Paludibacter propionicigenes showed the highest increase in relative abundance ratios in the presence of dyes (7.

Associative anticipatory learning and control of the cerebellar cortex based on the spike-timing-dependent plasticity of the parallel fiber-Purkinje cell synapses.

Time delays are inevitable in the neural processing of sensorimotor systems; small delays can cause severe damage to movement accuracy and stability. It is strongly suggested that the cerebellum compensates for delays in neural signal processing and performs predictive control. Neural computational theories have explored concepts of the internal models of control objects-believed to avoid delays by providing internal feedback information-although there has been no clear relevance to neural processing.

Effects of supplemental β-carotene on colostral immunoglobulin and plasma β-carotene and immunoglobulin in Japanese Black cows.

Data from 26 Japanese Black cows were collected to clarify the effects of supplemental β-carotene on colostral immunoglobulin (Ig) and plasma β-carotene and Ig in the cows. Cows were assigned to control or β-carotene groups from 21 days before the expected calving date to 60 days after parturition. Supplemental β-carotene was provided at 500 mg/day in the β-carotene group.

Effects of β-carotene-enriched dry carrots on β-carotene status and colostral immunoglobulin in β-carotene-deficient Japanese Black cows.

Data from 18 β-carotene-deficient Japanese Black cows were collected to clarify the effects of feeding β-carotene-enriched dry carrots on β-carotene status and colostral immunoglobulin (Ig) in cows. Cows were assigned to control or carrot groups from 3 weeks before the expected calving date to parturition, and supplemental β-carotene from dry carrots was 138 mg/day in the carrot group. Plasma β-carotene concentrations in the control and carrot groups at parturition were 95 and 120 μg/dL, and feeding dry carrots slightly improved plasma β-carotene at parturition.

A theory of cerebellar cortex and adaptive motor control based on two types of universal function approximation capability.

Lesions of the cerebellum result in large errors in movements. The cerebellum adaptively controls the strength and timing of motor command signals depending on the internal and external environments of movements. The present theory describes how the cerebellar cortex can control signals for accurate and timed movements.

Organoclays in water cause expansion that facilitates caffeine adsorption.

This study investigates the adsorption of caffeine in water on organically modified clays (a natural montmorillonite and synthetic saponite, which are smectite group of layered clay minerals). The organoclays were prepared by cation-exchange reactions of benzylammonium and neostigmine with interlayer exchangeable cations in the clay minerals. Although less caffeine was uptaken on neostigmine-modified clays than on raw clay minerals, uptake was increased by adding benzylammonium to the clays.

New supervised learning theory applied to cerebellar modeling for suppression of variability of saccade end points.

A new supervised learning theory is proposed for a hierarchical neural network with a single hidden layer of threshold units, which can approximate any continuous transformation, and applied to a cerebellar function to suppress the end-point variability of saccades. In motor systems, feedback control can reduce noise effects if the noise is added in a pathway from a motor center to a peripheral effector; however, it cannot reduce noise effects if the noise is generated in the motor center itself: a new control scheme is necessary for such noise. The cerebellar cortex is well known as a supervised learning system, and a novel theory of cerebellar cortical function developed in this study can explain the capability of the cerebellum to feedforwardly reduce noise effects, such as end-point variability of saccades.

Efficacy and safety of pramipexole in Japanese patients with primary restless legs syndrome: A polysomnographic randomized, double-blind, placebo-controlled study.

Objective: To evaluate the efficacy of pramipexole on polysomnographic measures, patient ratings and a clinical rating in Japanese patients with primary restless legs syndrome (RLS).

Methods: Patients with moderate to severe RLS having periodic limb movements in bed index (PLMI)>or=5 were randomly assigned to receive pramipexole or placebo in a 6-week, double-blind, placebo-controlled study with forced titration from 0.125 to 0.

Some perspectives on saccade adaptation.

The saccadic system is an ideal model for the study of how the brain optimizes its motor behavior. Here we review some recent research that points to exciting new areas of investigation relative to the multiple time scales of and the influence of context and consolidation on motor learning. These findings suggest new ways of thinking about the processes that underlie the short-term adaptive mechanisms that maintain accuracy of eye movements and so ensure optimal vision.

The effect of one-dose package on medication adherence for the elderly care in Japan.

Unlabelled: Deterioration of the medication adherence for elderly could result in wasteful medical expenditure in a long-term span as well as aggravating the patient's medical condition.

Objective: This study surveyed the effect of one-dose package medication made up by a pharmacist on the patient's behavior towards medication, what is expected to be one of the measures to improve the medication adherence for elderly.

Methods: With support activity of the Pharmacist Association in Ueda-city in Nagano Prefecture, Japan, the survey form of one-dose package was sent to 86 pharmacy directors located in Ueda-city.

Feed-forward associative learning for volitional movement control.

One of the most difficult problems in motor learning is determining the source of a learning signal, sometimes called an error signal. This problem is hidden in the adaptations of simple reflexive movements by attributing its source to sensory organs. The feed-forward associative motor learning theory proposed here attributes the source to the movement system itself.

Selective and delay adaptation of human saccades.

The consistently triggered step back of a target during primary saccades of a human subject induced a gradual change in gain, the ratio of the saccade amplitude to the target eccentricity. After a few hundred trials, subjects were able to foveate the displaced target in a single saccade. Presentation of a displaced target showed that human memory guided saccades have gain adaptation just like the well-established adaptation of visually guided saccades.