Publications by authors named "Masae Sonoda"
J Am Heart Assoc
November 2024
Article Synopsis
- Evolocumab, a monoclonal antibody approved for treating familial hypercholesterolemia (FH) and hypercholesterolemia, was evaluated in a real-world study in Japan, as data on its effectiveness and safety were previously limited.
- The study involved 3724 patients with various forms of FH and hypercholesterolemia over 104 weeks, measuring both safety (incidences of adverse reactions) and effectiveness (changes in LDL cholesterol levels).
- Results indicated that Evolocumab was well tolerated, showing significant reductions in LDL cholesterol levels, with low rates of serious adverse events, suggesting it is a viable treatment option for high-risk patients in Japan.
