Generative artificial intelligence model for simulating structural brain changes in schizophrenia.

Background: Recent advancements in generative artificial intelligence (AI) for image generation have presented significant opportunities for medical imaging, offering a promising way to generate realistic virtual medical images while ensuring patient privacy. The generation of a large number of virtual medical images through AI has the potential to augment training datasets for discriminative AI models, particularly in fields with limited data availability, such as neuroimaging. Current studies on generative AI in neuroimaging have mainly focused on disease discrimination; however, its potential for simulating complex phenomena in psychiatric disorders remains unknown.

Impacts of climate change on reproductive phenology in tropical rainforests of Southeast Asia.

In humid forests in Southeast Asia, many species from dozens of plant families flower gregariously and fruit synchronously at irregular multi-year intervals. Little is known about how climate change will impact these community-wide mass reproductive events. Here, we perform a comprehensive analysis of reproductive phenology and its environmental drivers based on a monthly reproductive phenology record from 210 species in 41 families in Peninsular Malaysia.

Interspecies Genomic Variation and Transcriptional Activeness of Secondary Metabolism-Related Genes in Section .

Filamentous fungi produce various bioactive compounds that are biosynthesized by sets of proteins encoded in biosynthesis gene clusters (BGCs). For an unknown reason, many BGCs are transcriptionally silent in laboratory conditions, which has hampered the discovery of novel fungal compounds. The transcriptional reactiveness of fungal secondary metabolism is not fully understood.

Draft Genome Sequence of IFM 58123.

Species of the Aspergillus section are taxonomically very complex. The taxonomic assignment of Aspergillus awamori is unclear. Here, we present the draft genome sequence of A.

[The efficacy of genioglossus advancement and uvulopalatopharyngoplasty for obstructive sleep apnea syndrome].

Objective: To evaluate the objective and subjective improvement after multilevel surgery, genioglossus advancement (GA) plus uvulopalatopharyngoplasty (UPPP) for the treatment of obstructive sleep apnea syndrome (OSAS).

Methods: GA and UPPP were undertaken in 24 patients with moderate and severe OSAS between January 2006 and December 2011. Epworth Sleepiness Scale (ESS) score, snoring, the feeling of having slept well and polysomnography were used for the evaluation of surgical outcomes.

Stapes fixation accompanied with abnormal facial nerve pathway.

The patient was a 52-year-old woman. She had been aware of her bilateral hearing loss since she was 20 years old. The hearing in her left ear started to deteriorate at the age of 49.

[Treatment experience of the metastatic renal cell carcinomas to the head and neck region in our department].

Renal cell carcinoma is the most common cancer known for multiple metastasis, but the frequency of metastasis to the head and neck region is low. We report two cases of metastatic renal cell carcinoma to the head and neck region. The case 1 is a 79 year-old man with renal cell carcinoma treatment six years later.

Enumerating tree-like chemical graphs with given upper and lower bounds on path frequencies.

Background: Enumeration of chemical graphs satisfying given constraints is one of the fundamental problems in chemoinformatics and bioinformatics since it leads to a variety of useful applications including structure determination of novel chemical compounds and drug design.

Results: In this paper, we consider the problem of enumerating all tree-like chemical graphs from a given set of feature vectors, which is specified by a pair of upper and lower feature vectors, where a feature vector represents the frequency of prescribed paths in a chemical compound to be constructed. This problem can be solved by applying the algorithm proposed by Ishida et al.

Involvement of the incudostapedial joint anomaly in conductive deafness.

Conclusion: The outcome of surgery depends on complexities of middle ear anomalies and definite diagnosis can only be achieved during exploratory tympanotomy. We must be aware that the pathology of the congenital ossicular anomalies is variable and careful surgery is needed for hearing improvement.

Objective: This study aimed to investigate congenital ossicular malformation.