The SIX5 Protein in f. sp. Acts as an Avirulence Effector toward Shallot ( L. Aggregatum Group).

f. sp. () causes basal rot disease in species, including onions ( L.

Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression.

The farnesoid X receptor (FXR; NR1H4) is a member of the nuclear receptor superfamily and regulates the expression of genes involved in enterohepatic circulation and the metabolism of bile acids. Based on functional analyses, nuclear receptors are divided into regions A-F. To explore the cofactors interacting with FXR, we performed a pull-down assay using GST-fused to the N-terminal A/B region and the C region, which are required for the ligand-independent transactivation and DNA-binding, respectively, of FXR, and nuclear extracts from HeLa cells.