Impact of temperature on the binding interaction between dsDNA and curcumin: An electrochemical study.

In this study, we investigated the binding mode between double-stranded deoxyribonucleic acid (dsDNA) and curcumin (CU) using differential pulse voltammetry (DPV), UV-Vis spectroscopy, and molecular docking. By employing these techniques, we predicted the binding within the minor groove region of dsDNA and CU. Significantly, we employed electrochemistry, specifically cyclic voltammetry (CV), to explore the temperature effect on the dsDNA and CU binding.

Development of an eco-friendly fluorescence nanosensor based on molecularly imprinted polymer on silica-carbon quantum dot for the rapid indoxacarb detection.

Rapid and efficient detection of indoxacarb (IXC), a common chemical contaminant, in environmental and biological samples is necessary. In this work, a modern optical sensor was developed for IXC, based on environmentally friendly molecularly imprinted polymer (MIP) coated on silica-carbon quantum dots (SiCQDs). A hydrothermal method was used to prepare highly fluorescence SiCQDs and, subsequently, MIP formed on surface (MIP@SiCQDs) using a sol-gel method.

A novel optical sensor based on carbon dots embedded molecularly imprinted silica for selective acetamiprid detection.

A molecularly imprinted polymer (MIP) on silane-doped carbon dots (Si-CDs) has been synthesized as a novel optical sensor for selective detection of acetamiprid (ACT). Highly fluorescence Si-CDs have been first prepared by hydrothermal method. Subsequently, MIP has been formed on the surface of Si-CDs (MIP@Si-CDs) by a sol-gel process.

Ingenious pH-sensitive etoposide loaded folic acid decorated mesoporous silica-carbon dot with carboxymethyl-βcyclodextrin gatekeeper for targeted drug delivery and imaging.

A new strategy is reported for the synthesis of label-free fluorescent mesoporous silica (MS) by the introduction of fluorescent carbon dots in the MSs (MSCDs) in this work. Etoposide (ETO) loaded MSCDs have been used as a drug model. Carboxymethyl β-cyclodextrin (CβCD) used as a gatekeeper agent was attached to amine-functionalized MSCDs to retain ETO molecules inside the nanocarrier.

Folate receptor-targeted multimodal fluorescence mesosilica nanoparticles for imaging, delivery palladium complex and in vitro G-quadruplex DNA interaction.

New folic acid-conjugated mesoporous silica nanoparticles were synthesized. The effect of calcination at 400°C on the fluorescence characteristics of mesoporous silica nanoparticles were studied in this work. The formed carbon dots (CDs) from calcination were used as the source of fluorescence.

Aptasensor based on fluorescence resonance energy transfer for the analysis of adenosine in urine samples of lung cancer patients.

A new aptasensor was designed for the analysis of adenosine based on fluorescence resonance energy transfer (FRET) between CdS quantum dot (QDs) as a donor and polypyrrole (Ppy) as an acceptor. The QDs were covalently bonded to anti-adenosine aptamer where its fluorescence was quenched by Ppy. When Ppy was replaced by adenosine, the fluorescence of QDs was restored and its intensity was proportional to the adenosine concentration.

Application of multivariate image analysis in QSPR study of 13C chemical shifts of naphthalene derivatives: a comparative study.

A new implemented QSPR method, whose descriptors achieved from bidimensional images, was applied for predicting (13)C NMR chemical shifts of 25 mono substituted naphthalenes. The resulted descriptors were subjected to principal component analysis (PCA) and the most significant principal components (PCs) were extracted. MIA-QSPR (multivariate image analysis applied to quantitative structure-property relationship) modeling was done by means of principal component regression (PCR) and principal component-artificial neural network (PC-ANN) methods.