Publications by Marziyeh Lotfi

Publications by authors named "Marziyeh Lotfi"

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Immunohistochemical assessment of MGMT expression and p53 mutation in glioblastoma multiforme.

Marziyeh Lotfi Sima Afsharnezhad Hamid Reza Raziee Kamran Ghaffarzadegan Samaneh Sharif

Tumori

May 2011

Aims And Background: The prognosis of glioblastoma multiforme (GBM) remains poor despite advances in surgery and adjuvant therapies. TP53 and O6-methylguanine-DNA methyltransferase (MGM) are tumor suppressor genes that are implicated in GBM resistance to radiation and chemotherapy. In order to assess the expression of the protein products of these two genes, 50 GBM samples were analyzed in this study.

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