Drug utilization study of antiepileptic drugs in the pediatric department, tertiary care hospital, Bangalore, India.

Objective: The main objective of the present study is to find out the loose links between prescription of medication and its utilization in the pediatric department, especially with drugs that belong to the antiepileptic medication category.

Methodology: This prospective observational study was carried out for 6 months in the Department of Pharmacy Practice, Tertiary Care Hospital, Bangalore. The study was conducted on 100 patients receiving antiepileptic medication.

Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial.

Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin (sNGAL) is superior to serum creatinine (sCr) in diagnosing early AKI. We compared the administration of hypertonic saline plus furosemide (HTS+F) versus hypertonic saline (HTS), using sCr and sNGAL to investigate kidney injury in patients with TBI.