Optimization of a novel antimicrobial nanocomposite films based on starch saffron corm incorporating nanoclay/lignin/extract using response surface methodology.

This study aimed to develop and optimize nanocomposite films for food packaging using starch saffron corm starch (SCS) combined with nanoclay and either lignin or saffron corm extract (SCE). Response surface methodology (RSM) with a face-centered central design was used to optimize clay, lignin, and SCE concentrations. The effects of these variables on the films' physical (thickness, water vapor permeability, color, and solubility), mechanical, and phenolic compound migration properties were evaluated.