Publications by authors named "Marzieh Mehri Tokmeh"
Article Synopsis
- The study focused on the anti-cancer effects of hypericin and naringenin on the Y79 retinoblastoma cell line, primarily investigating apoptosis, which is the process of programmed cell death.
- Using XTT and trypan blue assays, researchers determined the cytotoxic effects of both compounds, finding that hypericin was more effective in inducing cell death compared to naringenin after 24 and 48 hours of treatment.
- Real-time PCR analysis revealed that hypericin influences the Bax/Bcl-2 ratio to promote apoptosis, while naringenin did not produce a significant increase in the Bax levels, indicating no synergistic effect when both compounds were used together.
