Nomophobia among nursing students: prevalence and associated factors.

Nomophobia, or the fear of being without a mobile phone, has been linked to negative impacts on the physical, psychological, and academic well-being of students, including nursing students. While the prevalence of nomophobia and its associated factors vary across studies, limited research has focused on nursing students in Hamedan-Iran. This study aimed to determine the prevalence of nomophobia and its related factors among nursing students in Hamedan Province.

Northwest Iranian dermatophyte isolates: anthropophilic and geophilic.

Background And Purposes: The fungi known as dermatophytes are a group of keratinophilic agents responsible for superficial infections in humans and animals. Recognition of the species distribution and epidemiology of dermatophytosis may be helpful in the prevention and improve prophylactic measures. The present molecular epidemiology study sought to investigate the incidence of etiological agents causing dermatophytosis.

The role of long non-coding RNA LINC00839 in oral squamous cell carcinoma based on bioinformatics and experimental research.

This study explores the role of LINC00839 and its potential interaction with the miR-195-5p/cyclin E1 (CCNE1) axis in oral squamous cell carcinoma (OSCC). Using The Cancer Genome Atlas, we analyzed lncRNA, miRNA, and mRNA sequencing data for OSCC. Different online tools were applied to detect lncRNA-related miRNAs and their target mRNAs, forming a lncRNA/miRNA/mRNA axis.

Serum and Salivary Levels of Phosphate in Gastric and Colorectal Cancer Patients.

Objective: Gastrointestinal cancer is one of the most common causes of death worldwide. As there are no clinical symptoms at the beginning of the disease, the diagnosis can be delayed and the stage increased. Timely diagnosis is therefore crucial.

Bisphenol A concentration in canned fruits and vegetables and their risk assessment using Monte Carlo simulation in Iran.

Bisphenol A (BPA) is a chemical produced in large quantities for use primarily in the production of polycarbonate plastics, which has risks for human health. This study aimed to investigate BPA contents in canned fruit and vegetable samples using Gas Chromatography-Mass Spectrometry (GC-MS). Furthermore, health risks were assessed for Iranian adults and children using Monte Carlo simulations.

Determination of heavy metals, nitrate and nitrite in mineral and drinking bottled water in Tehran, Iran: A health risk assessment by Monte-Carlo simulation method.

Heavy metals, nitrate, and nitrite pose significant risks to public health and have raised substantial concern worldwide. This study aimed to investigate the content of nitrate, nitrite, and heavy metals, including Ba, Be, Ca, Fe, K, Li, Mg, Mn, Mo, and Na, in 30 bottled water brands in winter and summer in Tehran, Iran. Heavy metal contents in the samples were analyzed using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES), and nitrate and nitrite contents were analyzed using Ion Chromatography (IC).

Traditional vs. modified Ringer lactate-based del Nido cardioplegia impacts on clinical outcomes in patients undergoing coronary artery bypass grafting: Results from a prospective, randomized, blinded trial.

Introduction: Myocardial protection with cardioplegia is a crucial approach to mitigate myocardial damage during coronary bypass grafting surgery (CABG) with cardiopulmonary bypass (CPB). The major component of the del Nido cardioplegia solution, Plasma-Lyte A, is difficult to obtain in Iran due to high cost. The objective of the current study was to study if the lactated Ringer's solution as the base for del Nido solution (LR DN) usage is a viable option as a substitute for Plasma-Lyte A in adult patients presenting for CABG surgery.

Relative Forgiveness of Different Allopurinol Implementation Patterns in People with Gout and their Impact on Clinical Outcomes: a Simulation Study.

Background And Objective: Adherence to urate-lowering therapy among people with gout is poor, so it is important to understand which day-to-day medication-taking ('implementation') patterns are most likely to lead to suboptimal serum urate concentrations and worsen clinical outcomes. This study aimed to (1) determine the relative forgiveness (RF) of allopurinol with hypothetical and real-life implementation patterns in people with gout, (2) explore the use of RF as a means of identifying suboptimal implementation patterns, (3) assess the impact of suboptimal implementation patterns on clinical outcomes.

Methods: A simulation study was conducted using a pharmacokinetic-pharmacodynamic model for allopurinol and serum urate to determine the RF of allopurinol implementation patterns.

Wear, Material Transfer, and Electrocautery Damage Are Ubiquitous on CoCrMo Femoral Knee Retrievals.

Despite high total knee arthroplasty (TKA) survivorship after 10 years (92%-99%), a gap persists where patient satisfaction lags clinical success. Additionally, while cobalt chrome molybdenum (CoCrMo) use decreases in primary total hip arthroplasty, the alloy continues to be widely used in TKA femoral components. In vivo, CoCrMo degradation may be associated with adverse local tissue reactions (ALTR) and compared with the hip, the damage mechanisms that may release metal in the knee and the potential biological effects remain poorly understood.

Carotid intima-media thickness and risk of atherosclerosis in multiple sclerosis: A cross-sectional study.

Background: Multiple sclerosis (MS) is characterized by inflammation and demyelination in the central nervous system. Recent studies have suggested a potential association between MS and an increased risk of atherosclerosis, a systemic vascular disease involving arterial wall thickening. Understanding this relationship is crucial, given the heightened cardiovascular risk observed in MS patients.

Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice.

Objectives: Asthma is a complex inflammatory disorder with the infiltration of inflammatory cells in the lung airways. Saffron's active component, crocin, has been proven to possess anti-inflammatory and anti-oxidant effects. The objective of this current study was to explore the impact of crocin on NF-kB and nuclear erythroid 2-related factor 2 (Nrf2)/ heme oxygenase-1 (HO-1) signaling pathways in ovalbumin (OVA)-sensitized mice, aiming to understand its mechanism.

Effect of SpikoGen subunit vaccine administration during pregnancy on fetal development of rats.

Purpose: The effects of coronavirus disease 2019 vaccination on fertility and pregnancy have turned out to be a main topic of public attention. Inactivated or recombinant protein vaccines are a reliable and safe method but mostly suffer from weak immunogenicity just in case formulated with a suitable adjuvant. The purpose of this research was to assess the impacts of new SpikoGen subunit vaccine administration during pregnancy on organogenesis in the rat fetus, which is a novel achievement in teratogenesis studies.

Deep learning for 3D vascular segmentation in hierarchical phase contrast tomography: a case study on kidney.

Automated blood vessel segmentation is critical for biomedical image analysis, as vessel morphology changes are associated with numerous pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients, the scarcity of annotated public datasets, and the quality of images. Our goal is to provide a foundation on the topic and identify a robust baseline model for application to vascular segmentation using a new imaging modality, Hierarchical Phase-Contrast Tomography (HiP-CT).

Synergistic effect of curcumin and Piperine loaded Niosomal nanoparticles on acute pulmonary toxicity induced by Paraquat in mice.

Objective: Paraquat (PQ), a widely used non-selective herbicide, induces severe lung toxicity by promoting cell death and tissue necrosis through the generation of reactive oxygen species (ROS) and free radicals. This study aimed to develop and evaluate novel niosomal nanoparticles (NPs) encapsulating curcumin and piperine to mitigate PQ-induced acute pulmonary toxicity in Balb/c mice.

Methods: The NPs were prepared using non-ionic surfactants and cholesterol via the thin film hydration method.

Effect of Phytosterols on Serum Levels of C-Reactive Protein: A Time- and Dose-Response Meta-analysis of Randomized Controlled Trial.

Introduction: Phytosterols are recognized for their cholesterol-reducing effects and are commonly used as dietary supplements or added to foods due to their potential cardiovascular benefits. However, evidence regarding the impact of phytosterol supplementation on inflammatory markers remains inconclusive.

Aim: This systematic review and meta-analysis aim to evaluate the effect of phytosterols in reducing levels of C-reactive protein (CRP) and high-sensitivity CRP (hs-CRP).

Haves and have-nots: socioeconomic position improves accuracy of machine learning algorithms for predicting high-impact chronic pain.

Lower socioeconomic position (SEP) is associated with increased risk of developing chronic pain, experiencing more severe pain, and suffering greater pain-related disability. However, SEP is a multidimensional construct; there is a dearth of research on which SEP features are most strongly associated with high-impact chronic pain, the relative importance of SEP predictive features compared to established chronic pain correlates, and whether the relative importance of SEP predictive features differs by race and sex. This study used 3 machine learning algorithms to address these questions among adults in the 2019 National Health Interview Survey.

First Report on Salvia Sahendica Boiss & Buhs roots biocomponents characterization by GC-MS and HPLC and Antibacterial Potency.

Treatment of bacterial infections with antibiotic resistance is complicated. For this reason, new therapeutic methods are needed to control bacterial infections. Therefore, it is necessary to discover new antibiotics from medicinal plants that can destroy drug-resistant bacteria.

Long Non-Coding RNA and as a Promising Diagnostic and Prognostic Biomarker in Glioblastoma Multiforme.

Background: Glioblastoma multiforme (GBM) is one of the most invasive types of brain cancer. LncRNAs can be considered a new prognostic and diagnostic biomarker in GBM. This study comprehensively explored the interaction of lncRNAs with mRNAs in the TCGA database and proposed a novel promising biomarker with favorable diagnostic and prognostic values.

Psychometric properties of the multifactor leadership questionnaire when used in early-career pharmacists with provisional registration.

Background: The Multifactor Leadership Questionnaire (MLQ) is a validated instrument used to explore participants' perceptions of leadership and the Outcomes of leadership, participants' evaluation of and satisfaction with leadership and willingness to put in extra effort. The factor structure of MLQ varies across studies. The aim was to explore the psychometric properties of the MLQ for early-career pharmacists rating their preceptor's leadership.

Modeling of carbon dioxide absorption into aqueous alkanolamines using machine learning and response surface methodology.

This research focuses on modeling CO absorption into alkanolamine solvents using multilayer perceptron (MLP), radial basis function network (RBF), Support Vector Machine (SVM), networks, and response surface methodology (RSM). The parameters, including solvent density, mass fraction, temperature, liquid phase equilibrium constant, CO loading, and partial pressure of CO, were used as input factors in the models. In addition, the value of CO mass flux was considered as output in the models.

Online Plain Language Tool and Health Information Quality: A Randomized Clinical Trial.

Importance: Complex and ineffective health communication is a critical source of health inequity and occurs despite repeated policy directives to provide health information that is easy to understand and applies health literacy principles.

Objective: To evaluate the effectiveness of the Sydney Health Literacy Lab Health Literacy Editor, an easy-to-use online plain language tool that supports health information providers to apply health literacy guidelines to written health information.

Design, Setting, And Participants: This randomized clinical trial, conducted online in Australia from May 2023 to February 2024, included a convenience sample of health information providers with no previous experience using the Health Literacy Editor.

The suppressive effects of crocin from saffron on allergic airway inflammation through Drp1/Nfr1/Mfn2/Pgc1-alpha signaling pathway in mice.

Ethnopharmacological Relevance: Saffron is derived from the dried stigmas of Crocus sativus L., which was considered by ancient nations for food and medicinal purposes. In traditional medicine, the therapeutic use of Crocus sativus includes antispasmodic, antitussive and expectorant.