Publications by authors named "Maryse Tardieu"
Article Synopsis
- Studying coagulation in newborns and children is challenging because they have low levels of factors that promote clotting and inhibitors.
- The research compares thrombin generation in a pediatric group of 586 children to 166 adults using a specific assay method to assess coagulation.
- Results show that while children's coagulation potential is lower without thrombomodulin, it normalizes with the presence of thrombomodulin, indicating that their coagulation balance is effectively maintained.
Introduction: Recombinant factor IX Fc fusion protein (rFIXFc) is an extended half-life concentrate for the treatment of haemophilia B (HB). rFIXFc activity monitoring is crucial in several clinical situations. However, differences were observed between one-stage clotting (OSC) and chromogenic assays, but not for all factor IX (FIX) concentrations.
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